ACYCLOVIR 5% CREAM
For 5 g
Pharmacies pay
$44.96 filed
5 × $8.99159 per GM
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$56.70 estimated
$44.96 + $6.74 (15%) + $5.00 fee per fill = $56.70
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ACYCLOVIR 5% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as acyclovir.
FDA gives its dosage form as cream and its route as topical.
FDA lists 6 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Padagis Israel Pharmaceuticals Ltd and Sun Pharmaceutical Industries, Inc.
FDA lists it under 3 Established Pharmacologic Classes: Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor, Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor and Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor.
The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $44.96 for 5 g (5 × $8.99159 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
All 6 NDCs
- 00093-3630-20 · Teva Pharmaceuticals USA, Inc. · $8.99159 per GM · eff. 2026-09-23 filed
- 45802-0044-75 · Padagis Israel Pharmaceuticals Ltd · $8.99159 per GM · eff. 2026-09-23 filed
- 51672-1361-05 · Sun Pharmaceutical Industries, Inc. · $8.99159 per GM · eff. 2026-09-23 filed
- 62332-0423-05 · Alembic Pharmaceuticals Inc. · $8.99159 per GM · eff. 2026-09-23 filed
- 65162-0836-14 · Amneal Pharmaceuticals LLC · $8.99159 per GM · eff. 2026-09-23 filed
- 72578-0101-05 · Viona Pharmaceuticals Inc · $8.99159 per GM · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name acyclovir with ACYCLOVIR 5% CREAM.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ACYCLOVIR 5% CREAM this page | $8.99159 per GM filed | We don’t know yet |
| ACYCLOVIR 5% OINTMENT | $0.34585 to $0.52214 per GM filed | We don’t know yet |
| ACYCLOVIR 200 MG CAPSULE | $0.09773 per EA filed | We don’t know yet |
| ACYCLOVIR 200 MG/5 ML SUSP | $0.07643 per ML filed | We don’t know yet |
| ACYCLOVIR 400 MG TABLET | $0.09623 per EA filed | We don’t know yet |
| ACYCLOVIR 800 MG TABLET | $0.19403 per EA filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
The middle of its 6 NDCs’ NADAC prices is $8.99159 per GM filed.
Of the 3 other products in FDA’s Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor class priced per GM, 2 have a higher middle NADAC price and 1 a lower one. The one in the middle is PENCICLOVIR 1% CREAM, at $52.1538 per GM filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 5 g? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 5 g; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 5 g?
- NADAC prices this product per GM. The FDA NDC Directory’s package description gives 5 g in one package for all 6 NDCs of this product (“1 TUBE in 1 CARTON (0093-3630-20) / 5 g in 1 TUBE”), so the card starts at one package: 5 GM. Change it to match your prescription.
Related pages
Its pharmacologic classes
- Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor