ADAPALENE 0.1% CREAM

What it is

ADAPALENE 0.1% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as adapalene.

FDA gives its dosage form as cream and its route as topical.

Its labelers, the companies named on the label, are E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC and Padagis Israel Pharmaceuticals Ltd.

FDA’s Established Pharmacologic Class for it is Retinoid.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $128.45 for 45 g (45 × $2.85454 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

All 2 NDCs

• 00168-0424-46 · E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC · $2.85454 per GM · eff. 2026-09-23 filed
• 45802-0453-84 · Padagis Israel Pharmaceuticals Ltd · $2.85454 per GM · eff. 2026-09-23 filed

Other strengths, forms and brands

4 other products in the NADAC file share the FDA nonproprietary name adapalene with ADAPALENE 0.1% CREAM.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $2.85454 per GM filed.

Of the 23 other products in FDA’s Retinoid class priced per GM, 11 have a higher middle NADAC price and 12 a lower one. The one in the middle is TRETINOIN 0.025% GEL, at $2.50019 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $134.08 for 45 g, at an average of $2.9795 per GM in 2024 (2024-01-01 to 2024-12-31) for “Adapalene”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 9,624 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 45 g? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 45 g; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.