AVALIDE 150-12.5 MG TABLET
FDA nonproprietary name: irbesartan and hydrochlorothiazide
For 30 tablets
Pharmacies pay
$267.33 filed
30 × $8.91093 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$276.44 filed
30 × $9.21474 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.0× estimated
Medicare paid about what pharmacies pay.
Part D averages every strength and form sold under “Avalide” / “Irbesartan/Hydrochlorothiazide” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-10-22 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$312.43 estimated
$267.33 + $40.10 (15%) + $5.00 fee per fill = $312.43
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-10-22 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
AVALIDE 150-12.5 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as irbesartan and hydrochlorothiazide, under the trade name “Avalide”.
FDA gives its dosage form as tablet, film coated and its route as oral.
The labeler, the company named on the label, is Sanofi-Aventis U.S. LLC.
FDA lists it under 2 Established Pharmacologic Classes: Angiotensin 2 Receptor Blocker and Thiazide Diuretic.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00024-5855-30.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $267.33 for 30 tablets (30 × $8.91093 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2025-10-22. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 4, carried forward from the previous file.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2025-10-22. The file is new; the price is not.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.14881 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes · Carried-forward prices
The NDC
- 00024-5855-30 · Sanofi-Aventis U.S. LLC · $8.91093 per EA · eff. 2025-10-22 filed carried forward
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name irbesartan and hydrochlorothiazide with AVALIDE 150-12.5 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| AVALIDE 150-12.5 MG TABLET this page | $8.91093 per EA filed | $9.21474 per EA filed |
| IRBESARTAN-HYDROCHLOROTHIAZIDE 150-12.5 MG TB | $0.14881 per EA filed | $0.31241 per EA filed |
| IRBESARTAN-HYDROCHLOROTHIAZIDE 300-12.5 MG TB | $0.1881 per EA filed | $0.31241 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $8.91093 per EA filed.
Of the 107 other products in FDA’s Angiotensin 2 Receptor Blocker class priced per EA, 25 have a higher middle NADAC price and 82 a lower one. The one in the middle is CANDESARTAN-HYDROCHLOROTHIAZIDE 32-25 MG TAB, at $1.07781 per EA filed (eff. 2026-09-23).
Of the 68 other products in FDA’s Thiazide Diuretic class priced per EA, 7 have a higher middle NADAC price and 61 a lower one. The one in the middle is TELMISARTAN-HYDROCHLOROTHIAZIDE 40-12.5 MG TB, at $0.3567 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $276.44 for 30 tablets, at an average of $9.21474 per EA in 2024 (2024-01-01 to 2024-12-31) for “Avalide” and “Irbesartan/Hydrochlorothiazide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,141 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: IRBESARTAN-HYDROCHLOROTHIAZIDE 150-12.5 MG TB. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for AVALIDE 150-12.5 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Avalide / Irbesartan/Hydrochlorothiazide: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
Related pages
Its pharmacologic classes
Related in the same class
- LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB
- VALSARTAN-HYDROCHLOROTHIAZIDE 160-12.5 MG TAB
- OLMESARTAN-HYDROCHLOROTHIAZIDE 20-12.5 MG TAB
- MICARDIS HCT 40-12.5 MG TABLET
- TRIBENZOR 40-10-25 MG TABLET