BETOPTIC S 0.25% EYE DROP

What it is

BETOPTIC S 0.25% EYE DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as betaxolol hydrochloride, under the trade name “Betoptic S”.

FDA gives its dosage form as suspension/ drops and its route as ophthalmic.

The labeler, the company named on the label, is Novartis Pharmaceuticals Corporation.

FDA’s Established Pharmacologic Class for it is beta-Adrenergic Blocker.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $42.62 – $42.88 for 1 mL, depending on the NDC ($42.62424 to $42.87902 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-07. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.

The NADAC of all 2 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-01-07. The file is new; the price is not.

What NADAC measures · NADAC explanation codes · Carried-forward prices

All 2 NDCs

• 00078-0729-10 · Novartis Pharmaceuticals Corporation · $42.62424 per ML · eff. 2026-01-07 filed carried forward
• 00078-0729-15 · Novartis Pharmaceuticals Corporation · $42.87902 per ML · eff. 2026-01-07 filed carried forward

Other strengths, forms and brands

3 other products in the NADAC file share the FDA nonproprietary name betaxolol hydrochloride with BETOPTIC S 0.25% EYE DROP.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-11-19, 2026-01-07, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $42.62424 per ML filed.

Of the 19 other products in FDA’s beta-Adrenergic Blocker class priced per ML, 1 has a higher middle NADAC price and 18 a lower one. The one in the middle is TIMOLOL 0.25% GEL-SOLUTION, at $6.37609 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-07, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $35.61 for 1 mL, at an average of $35.60967 per ML in 2024 (2024-01-01 to 2024-12-31) for “Betoptic S” and “Betaxolol HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 7,033 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
• Which NDC (the 11-digit number on the package) is this? Pharmacies pay $42.62424 to $42.87902 per ML for this product, depending on the NDC.
• How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.