BUTRANS 15 MCG/HR PATCH
FDA nonproprietary name: buprenorphine
For 1 patch
Pharmacies pay
$124.62 filed
1 × $124.62313 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$102.43 filed
1 × $102.43317 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.82× estimated
Medicare paid 18% less than pharmacies pay.
Part D averages every strength and form sold under “Butrans” / “Buprenorphine” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$148.31 estimated
$124.62 + $18.69 (15%) + $5.00 fee per fill = $148.31
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
BUTRANS 15 MCG/HR PATCH is how the CMS NADAC file names this product. The FDA NDC Directory lists it as buprenorphine, under the trade name “Butrans”.
FDA gives its dosage form as patch, extended release and its route as transdermal.
The labeler, the company named on the label, is Knoa Pharma LLC.
FDA’s Established Pharmacologic Class for it is Partial Opioid Agonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 59011-0758-04.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $124.62 for 1 patch (1 × $124.62313 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $53.7821 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes
The NDC
- 59011-0758-04 · Knoa Pharma LLC · $124.62313 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
11 other products in the NADAC file share the FDA nonproprietary name buprenorphine with BUTRANS 15 MCG/HR PATCH.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| BUPRENORPHINE 2 MG TABLET SL | $0.27676 per EA filed | We don’t know yet |
| BUPRENORPHINE 5 MCG/HR PATCH | $23.44849 per EA filed | $61.65324 per EA filed |
| BUPRENORPHINE 7.5 MCG/HR PATCH | $37.67882 per EA filed | $61.65324 per EA filed |
| BUPRENORPHINE 8 MG TABLET SL | $0.57141 per EA filed | We don’t know yet |
| BUPRENORPHINE 10 MCG/HR PATCH | $32.52934 per EA filed | $61.65324 per EA filed |
| BUPRENORPHINE 15 MCG/HR PATCH | $53.7821 per EA filed | $61.65324 per EA filed |
| BUPRENORPHINE 20 MCG/HR PATCH | $58.8288 per EA filed | $61.65324 per EA filed |
| BUTRANS 5 MCG/HR PATCH | $48.86594 per EA filed | $102.43317 per EA filed |
| BUTRANS 7.5 MCG/HR PATCH | $68.82197 per EA filed | $102.43317 per EA filed |
| BUTRANS 10 MCG/HR PATCH | $73.60023 per EA filed | $102.43317 per EA filed |
| BUTRANS 15 MCG/HR PATCH this page | $124.62313 per EA filed | $102.43317 per EA filed |
| BUTRANS 20 MCG/HR PATCH | $131.09389 per EA filed | $102.43317 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $124.62313 per EA filed.
Of the 34 other products in FDA’s Partial Opioid Agonist class priced per EA, 1 has a higher middle NADAC price and 33 a lower one. The one in the middle is ZUBSOLV 5.7-1.4 MG TABLET SL, at $10.54312 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $102.43 for 1 patch, at an average of $102.43317 per EA in 2024 (2024-01-01 to 2024-12-31) for “Butrans” and “Buprenorphine”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 25,786 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 patch? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for BUTRANS 15 MCG/HR PATCH labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Butrans / Buprenorphine: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
- Why does this page start at 1 patch?
- NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “PATCH, EXTENDED RELEASE” with route “TRANSDERMAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. So the card starts at 1 patch, priced per patch, rather than guess how many make up a fill; change it to match your prescription.