Why does this page start at 1 unit (EA)?

NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION” with route “INTRAVENOUS”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.

CATHFLO ACTIVASE 2 MG VIAL

FDA nonproprietary name: alteplase

For 1 unit (EA)

Pharmacies pay

$186.38 filed

1 × $186.3796 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part B pays

$196.83 derived

1 × $196.832 per EA, Part B limit

Medicare's price is not your price.

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

The spread

1.1× derived

Medicare pays 1.1× what pharmacies pay.

Derived because only one labeler, Genentech, Inc., is listed for HCPCS J2997 on the CMS crosswalk, so the payment limit comes from that company’s own products under the code, not an average across companies.

OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-01 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)

Cost-plus estimate

$219.34 estimated

$186.38 + $27.96 (15%) + $5.00 fee per fill = $219.34

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-01 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

CATHFLO ACTIVASE 2 MG VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as alteplase, under the trade name “Cathflo Activase”.

FDA gives its dosage form as injection, powder, lyophilized, for solution and its route as intravenous.

The labeler, the company named on the label, is Genentech, Inc.

FDA lists no Established Pharmacologic Class for it.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 50242-0041-64.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $186.38 for 1 unit (EA) (1 × $186.3796 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-01. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.

This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-01-01. The file is new; the price is not.

What NADAC measures · NADAC explanation codes · Carried-forward prices

The NDC

50242-0041-64 · Genentech, Inc. · $186.3796 per EA · eff. 2026-01-01 filed carried forward

What Medicare paid

Medicare Part B’s payment limit for HCPCS J2997, for 2026-10-01 to 2026-12-31, comes to $196.83 for 1 unit (EA), or $196.832 per EA once converted to NADAC’s unit for this product.

Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.

The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $19.6832 per 1 MG.

Medicare's price is not your price.

What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why does this page start at 1 unit (EA)?: NADAC prices this product per EA, and the FDA NDC Directory lists its NDC as dosage form “INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION” with route “INTRAVENOUS”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.