CHLORTHALIDONE 25 MG TABLET
For 30 tablets
Pharmacies pay
$2.23 filed
30 × $0.07433 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$7.26 filed
30 × $0.24186 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
3.3× estimated
Medicare paid 3.3× what pharmacies pay.
Part D averages every strength and form sold under “Chlorthalidone” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$7.56 estimated
$2.23 + $0.33 (15%) + $5.00 fee per fill = $7.56
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CHLORTHALIDONE 25 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as chlorthalidone, under the trade name “CHLORTHALIDONE CHLORTHALIDONE”.
FDA gives its dosage form as tablet and its route as oral.
FDA lists 18 labelers (the companies named on the label) for its NDCs, among them Mylan Pharmaceuticals Inc., Major Pharmaceuticals and Northstar Rx LLC.
FDA’s Established Pharmacologic Class for it is Thiazide-like Diuretic.
The NADAC file of 2026-10-14 prices it under 37 NDCs (National Drug Codes); the FDA directory lists 33 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $2.23 for 30 tablets (30 × $0.07433 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 18 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Dr. Reddy's Laboratories Inc. | 4 | $0.07433 per EA filed |
| Rising Pharma Holdings, Inc. | 4 | $0.07433 per EA filed |
| Major Pharmaceuticals | 3 | $0.07433 per EA filed |
| American Health Packaging | 2 | $0.07433 per EA filed |
| Ascend Laboratories, LLC | 2 | $0.07433 per EA filed |
| Chartwell RX, LLC | 2 | $0.07433 per EA filed |
| Lifestar Pharma LLC | 2 | $0.07433 per EA filed |
| Mylan Pharmaceuticals Inc. | 2 | $0.07433 per EA filed |
| Nivagen Pharmaceuticals, INC. | 2 | $0.07433 per EA filed |
| Zydus Pharmaceuticals USA Inc. | 2 | $0.07433 per EA filed |
| Ajanta Pharma USA Inc. | 1 | $0.07433 per EA filed |
| Alembic Pharmaceuticals Inc. | 1 | $0.07433 per EA filed |
| Amneal Pharmaceuticals LLC | 1 | $0.07433 per EA filed |
| AvPAK | 1 | $0.07433 per EA filed |
| Mylan Institutional Inc. | 1 | $0.07433 per EA filed |
| Northstar Rx LLC. | 1 | $0.07433 per EA filed |
| Sun Pharmaceutical Industries, Inc. | 1 | $0.07433 per EA filed |
| Unichem Pharmaceuticals (USA), Inc. | 1 | $0.07433 per EA filed |
| Not listed as a package in the FDA directory | 4 | $0.07433 per EA filed |
All 37 NDCs, with labeler and price
- 00378-0222-01 · Mylan Pharmaceuticals Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 00378-0222-10 · Mylan Pharmaceuticals Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 00904-6900-04 · Major Pharmaceuticals · $0.07433 per EA · eff. 2026-09-23 filed
- 00904-6900-61 · Major Pharmaceuticals · $0.07433 per EA · eff. 2026-09-23 filed
- 00904-7583-61 · Major Pharmaceuticals · $0.07433 per EA · eff. 2026-09-23 filed
- 16714-0128-01 · Northstar Rx LLC. · $0.07433 per EA · eff. 2026-09-23 filed
- 27241-0216-01 · Ajanta Pharma USA Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 29300-0333-01 · Unichem Pharmaceuticals (USA), Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 43598-0170-01 · Dr. Reddy's Laboratories Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 43598-0170-10 · Dr. Reddy's Laboratories Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 43598-0719-01 · Dr. Reddy's Laboratories Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 43598-0719-10 · Dr. Reddy's Laboratories Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 50268-0167-11 · not listed as a package in the FDA directory · $0.07433 per EA · eff. 2026-09-23 filed
- 50268-0167-15 · AvPAK · $0.07433 per EA · eff. 2026-09-23 filed
- 51079-0058-01 · not listed as a package in the FDA directory · $0.07433 per EA · eff. 2026-09-23 filed
- 51079-0058-20 · Mylan Institutional Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 57664-0648-88 · Sun Pharmaceutical Industries, Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 60687-0317-01 · American Health Packaging · $0.07433 per EA · eff. 2026-09-23 filed
- 60687-0317-11 · not listed as a package in the FDA directory · $0.07433 per EA · eff. 2026-09-23 filed
- 60687-0317-25 · American Health Packaging · $0.07433 per EA · eff. 2026-09-23 filed
- 60687-0317-95 · not listed as a package in the FDA directory · $0.07433 per EA · eff. 2026-09-23 filed
- 62135-0505-30 · Chartwell RX, LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 62135-0505-90 · Chartwell RX, LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 62332-0676-31 · Alembic Pharmaceuticals Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 64980-0303-01 · Rising Pharma Holdings, Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 64980-0303-10 · Rising Pharma Holdings, Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 64980-0599-01 · Rising Pharma Holdings, Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 64980-0599-10 · Rising Pharma Holdings, Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 65162-0247-09 · Amneal Pharmaceuticals LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 67877-0696-01 · Ascend Laboratories, LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 67877-0696-10 · Ascend Laboratories, LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 68382-0970-01 · Zydus Pharmaceuticals USA Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 68382-0970-10 · Zydus Pharmaceuticals USA Inc. · $0.07433 per EA · eff. 2026-09-23 filed
- 70756-0011-11 · Lifestar Pharma LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 70756-0011-12 · Lifestar Pharma LLC · $0.07433 per EA · eff. 2026-09-23 filed
- 75834-0109-01 · Nivagen Pharmaceuticals, INC. · $0.07433 per EA · eff. 2026-09-23 filed
- 75834-0109-10 · Nivagen Pharmaceuticals, INC. · $0.07433 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name chlorthalidone with CHLORTHALIDONE 25 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CHLORTHALIDONE 25 MG TABLET this page | $0.07433 per EA filed | $0.24186 per EA filed |
| CHLORTHALIDONE 50 MG TABLET | $0.12175 per EA filed | $0.24186 per EA filed |
| HEMICLOR 12.5 MG TABLET | $0.95713 per EA filed | We don’t know yet |
| THALITONE 15 MG TABLET | $3.54226 per EA filed | $3.56148 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 37 NDCs’ NADAC prices is $0.07433 per EA filed.
Of the 12 other products in FDA’s Thiazide-like Diuretic class priced per EA, 12 have a higher middle NADAC price and 0 a lower one. The one in the middle is METOLAZONE 5 MG TABLET, at $0.23919 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $7.26 for 30 tablets, at an average of $0.24186 per EA in 2024 (2024-01-01 to 2024-12-31) for “Chlorthalidone”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 2,941,224 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for CHLORTHALIDONE 25 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Chlorthalidone / Chlorthalidone: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Related pages
Its pharmacologic class
Related in the same class
- METOLAZONE 10 MG TABLET
- INDAPAMIDE 1.25 MG TABLET
- ATENOLOL-CHLORTHALIDONE 100-25
- EDARBYCLOR 40-12.5 MG TABLET