CIPROFLOXACIN HCL 500 MG TAB
For 30 tablets
Pharmacies pay
$3.69 filed
30 × $0.12284 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$16.61 filed
30 × $0.55352 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
4.5× estimated
Medicare paid 4.5× what pharmacies pay.
Part D averages every strength and form sold under “Ciprofloxacin HCl*” / “Ciprofloxacin HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$9.24 estimated
$3.69 + $0.55 (15%) + $5.00 fee per fill = $9.24
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CIPROFLOXACIN HCL 500 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “ciprofloxacin”, “ciprofloxacin hydrochloride” and “ciprofolxacin”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “tablet, film coated” and “tablet” and its route as oral.
FDA lists 10 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Major Pharmaceuticals and Teva Pharmaceuticals USA, Inc.
FDA’s Established Pharmacologic Class for it is Fluoroquinolone Antibacterial.
The NADAC file of 2026-10-14 prices it under 26 NDCs (National Drug Codes); the FDA directory lists 23 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $3.69 for 30 tablets (30 × $0.12284 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 10 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Aurobindo Pharma Limited | 6 | $0.12284 per EA filed |
| Chartwell RX, LLC. | 3 | $0.12284 per EA filed |
| American Health Packaging | 2 | $0.12284 per EA filed |
| Carlsbad Technology, Inc. | 2 | $0.12284 per EA filed |
| Major Pharmaceuticals | 2 | $0.12284 per EA filed |
| Rising Pharma Holdings, Inc. | 2 | $0.12284 per EA filed |
| Solco Healthcare US, LLC | 2 | $0.12284 per EA filed |
| Westminster Pharmaceuticals, LLC | 2 | $0.12284 per EA filed |
| Hikma Pharmaceuticals USA Inc. | 1 | $0.12284 per EA filed |
| Teva Pharmaceuticals USA, Inc. | 1 | $0.12284 per EA filed |
| Not listed as a package in the FDA directory | 3 | $0.12284 per EA filed |
All 26 NDCs, with labeler and price
- 00143-9928-01 · Hikma Pharmaceuticals USA Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 00904-7243-61 · Major Pharmaceuticals · $0.12284 per EA · eff. 2026-09-23 filed
- 00904-7243-95 · Major Pharmaceuticals · $0.12284 per EA · eff. 2026-09-23 filed
- 13107-0077-01 · not listed as a package in the FDA directory · $0.12284 per EA · eff. 2026-09-23 filed
- 16252-0515-01 · Teva Pharmaceuticals USA, Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 16571-0412-10 · Rising Pharma Holdings, Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 16571-0412-50 · Rising Pharma Holdings, Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 43547-0689-10 · Solco Healthcare US, LLC · $0.12284 per EA · eff. 2026-09-23 filed
- 43547-0689-50 · Solco Healthcare US, LLC · $0.12284 per EA · eff. 2026-09-23 filed
- 59651-0867-01 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 59651-0867-05 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 59651-0977-01 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 59651-0977-05 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 60687-0860-01 · American Health Packaging · $0.12284 per EA · eff. 2026-09-23 filed
- 60687-0860-11 · not listed as a package in the FDA directory · $0.12284 per EA · eff. 2026-09-23 filed
- 60687-0947-01 · American Health Packaging · $0.12284 per EA · eff. 2026-09-23 filed
- 60687-0947-11 · not listed as a package in the FDA directory · $0.12284 per EA · eff. 2026-09-23 filed
- 61442-0223-01 · Carlsbad Technology, Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 61442-0223-05 · Carlsbad Technology, Inc. · $0.12284 per EA · eff. 2026-09-23 filed
- 62135-0309-01 · Chartwell RX, LLC. · $0.12284 per EA · eff. 2026-09-23 filed
- 62135-0309-05 · Chartwell RX, LLC. · $0.12284 per EA · eff. 2026-09-23 filed
- 62135-0309-20 · Chartwell RX, LLC. · $0.12284 per EA · eff. 2026-09-23 filed
- 65862-0077-01 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 65862-0077-05 · Aurobindo Pharma Limited · $0.12284 per EA · eff. 2026-09-23 filed
- 69367-0386-01 · Westminster Pharmaceuticals, LLC · $0.12284 per EA · eff. 2026-09-23 filed
- 69367-0386-05 · Westminster Pharmaceuticals, LLC · $0.12284 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share an FDA nonproprietary name with CIPROFLOXACIN HCL 500 MG TAB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CILOXAN 0.3% OINTMENT | $74.31212 per GM filed | $75.76001 per GM filed |
| CIPRO 5% SUSPENSION | $1.24862 per ML filed | We don’t know yet |
| CIPRO 10% SUSPENSION | $1.45528 per ML filed | We don’t know yet |
| CIPROFLOXACIN 0.2% OTIC SOLN | $6.35188 per EA filed | We don’t know yet |
| CIPROFLOXACIN 0.3% EYE DROP | $0.79641 to $3.07806 per ML filed | We don’t know yet |
| CIPROFLOXACIN HCL 250 MG TAB | $0.0751 per EA filed | $0.55352 per EA filed |
| CIPROFLOXACIN HCL 500 MG TAB this page | $0.12284 per EA filed | $0.55352 per EA filed |
| CIPROFLOXACIN HCL 750 MG TAB | $0.25021 per EA filed | $0.55352 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 26 NDCs’ NADAC prices is $0.12284 per EA filed.
Of the 4 other products in FDA’s Fluoroquinolone Antibacterial class priced per EA, 3 have a higher middle NADAC price and 1 a lower one. The one in the middle is CIPROFLOXACIN HCL 750 MG TAB, at $0.25021 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $16.61 for 30 tablets, at an average of $0.55352 per EA in 2024 (2024-01-01 to 2024-12-31) for “Ciprofloxacin HCl*” and “Ciprofloxacin HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 4,856,922 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
2 of the product’s 26 NDCs have this Medicare figure; the other 24 do not, and the interactive card says why for each.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for CIPROFLOXACIN HCL 500 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Ciprofloxacin HCl* / Ciprofloxacin HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (4 of the 5 the name join matched); NDCs of another route or with no known FDA route do not.