COMBIPATCH 0.05-0.25 MG PTCH

What it is

COMBIPATCH 0.05-0.25 MG PTCH is how the CMS NADAC file names this product. The FDA NDC Directory lists it as estradiol/norethindrone acetate transdermal system, under the trade name “CombiPatch (estradiol/norethindrone acetate transdermal system)”.

FDA gives its dosage form as patch, extended release and its route as transdermal.

The labeler, the company named on the label, is Noven Therapeutics, LLC.

FDA lists it under 2 Established Pharmacologic Classes: Estrogen and Progestin.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes); the FDA directory lists 1 of them.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $31.79 for 1 patch (1 × $31.7862 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · NADAC explanation codes

All 2 NDCs

• 68968-0525-01 · not listed as a package in the FDA directory · $31.7862 per EA · eff. 2026-09-23 filed
• 68968-0525-08 · Noven Therapeutics, LLC · $31.7862 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

1 other product in the NADAC file shares the FDA nonproprietary name estradiol/norethindrone acetate transdermal system with COMBIPATCH 0.05-0.25 MG PTCH.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $31.7862 per EA filed.

Of the 104 other products in FDA’s Estrogen class priced per EA, 16 have a higher middle NADAC price and 88 a lower one. The one in the middle is LYLLANA 0.075 MG PATCH, at $8.11285 per EA filed (eff. 2026-09-23).

Of the 65 other products in FDA’s Progestin class priced per EA, 12 have a higher middle NADAC price and 53 a lower one. The one in the middle is NORETHIN-ETH ESTRAD 1 MG-5 MCG, at $0.57994 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $29.89 for 1 patch, at an average of $29.88513 per EA in 2024 (2024-01-01 to 2024-12-31) for “Combipatch” and “Estradiol/Norethindrone Acet”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 13,387 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 patch? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.