CYANOCOBALAMIN 1,000 MCG/ML VL
For 1 mL
Pharmacies pay
$1.47 – $2.97 filed
1 × $1.47387 to $2.97018 per ML (the 17 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$0.65 derived
1 × $0.648 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.22× – 0.44× estimated
Medicare pays between 0.22× and 0.44× what pharmacies pay, depending on the NDC.
14 labelers share HCPCS J3420 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$6.69 – $8.42 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CYANOCOBALAMIN 1,000 MCG/ML VL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as cyanocobalamin.
FDA gives its dosage form as “injection” and “injection, solution” and its route as “intramuscular; subcutaneous”, “subcutaneous” and “intramuscular”.
FDA lists 11 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., American Regent, Inc. and Sagent Pharmaceuticals.
FDA’s Established Pharmacologic Class for it is Vitamin B12.
The NADAC file of 2026-10-14 prices it under 17 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.47 – $2.97 for 1 mL, depending on the NDC ($1.47387 to $2.97018 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The 11 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Meitheal Pharmaceuticals Inc. | 4 | $1.47387 per ML filed |
| BluePoint Laboratories | 2 | $1.47387 per ML filed |
| Fresenius Kabi USA, LLC | 2 | $1.47387 per ML filed |
| Vitruvias Therapeutics | 2 | $1.47387 to $2.97018 per ML filed |
| American Regent, Inc. | 1 | $1.47387 per ML filed |
| Hikma Pharmaceuticals USA Inc. | 1 | $1.47387 per ML filed |
| Lifestar Pharma LLC | 1 | $1.47387 per ML filed |
| NorthStar RxLLC | 1 | $1.47387 per ML filed |
| SOLA Pharmaceuticals | 1 | $1.47387 per ML filed |
| Sagent Pharmaceuticals | 1 | $1.47387 per ML filed |
| Somerset Therapeutics, LLC | 1 | $1.47387 per ML filed |
All 17 NDCs, with labeler and price
- 00143-9621-25 · Hikma Pharmaceuticals USA Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 00517-0031-25 · American Regent, Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 25021-0502-01 · Sagent Pharmaceuticals · $1.47387 per ML · eff. 2026-09-23 filed
- 63323-0044-01 · Fresenius Kabi USA, LLC · $1.47387 per ML · eff. 2026-09-23 filed
- 63323-0044-44 · Fresenius Kabi USA, LLC · $1.47387 per ML · eff. 2026-09-23 filed
- 68001-0542-60 · BluePoint Laboratories · $1.47387 per ML · eff. 2026-09-23 filed
- 68001-0640-60 · BluePoint Laboratories · $1.47387 per ML · eff. 2026-09-23 filed
- 69680-0112-10 · Vitruvias Therapeutics · $2.97018 per ML · eff. 2026-09-23 filed
- 69680-0112-25 · Vitruvias Therapeutics · $1.47387 per ML · eff. 2026-09-23 filed
- 70069-0005-10 · Somerset Therapeutics, LLC · $1.47387 per ML · eff. 2026-09-23 filed
- 70512-0840-25 · SOLA Pharmaceuticals · $1.47387 per ML · eff. 2026-09-23 filed
- 70756-0635-25 · Lifestar Pharma LLC · $1.47387 per ML · eff. 2026-09-23 filed
- 71288-0300-02 · Meitheal Pharmaceuticals Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 71288-0300-92 · Meitheal Pharmaceuticals Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 71288-0303-02 · Meitheal Pharmaceuticals Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 71288-0303-92 · Meitheal Pharmaceuticals Inc. · $1.47387 per ML · eff. 2026-09-23 filed
- 72603-0650-25 · NorthStar RxLLC · $1.47387 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name cyanocobalamin with CYANOCOBALAMIN 1,000 MCG/ML VL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CYANOCOBALAMIN 1,000 MCG/ML VL this page | $1.47387 to $2.97018 per ML filed | $0.648 per ML derived |
| CYANOCOBALAMIN 10,000 MCG/10 ML | $0.73861 to $2.97018 per ML filed | $0.648 per ML derived |
| CYANOCOBALAMIN 30,000 MCG/30 ML | $0.32805 to $0.78707 per ML filed | $0.648 per ML derived |
| CYANOCOBALAMIN 500 MCG SPRAY | $95.90838 per EA filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 17 NDCs’ NADAC prices is $1.47387 per ML filed.
Of the 4 other products in FDA’s Vitamin B12 class priced per ML, 1 has a higher middle NADAC price and 3 a lower one. The one in the middle is MULTIVIT-FLUOR 0.25 MG/ML DROP, at $0.17794 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J3420, for 2026-10-01 to 2026-12-31, comes to $0.65 for 1 mL, or $0.648 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.1296 per 1000 MCG.
15 of the product’s 17 NDCs have this Medicare figure; the other 2 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $1.47387 to $2.97018 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, 17 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00143-9621-25 (“25 VIAL in 1 BOX (0143-9621-25) / 1 mL in 1 VIAL (0143-9621-01)”) is a box of 25 vials, 25 mL in all. So the card starts at one unit: 1 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- PRENATAL VITAMIN PLUS LOW IRON
- M-NATAL PLUS TABLET
- VITAFOL ULTRA SOFTGEL
- PRENATE MINI SOFTGEL
- PNV-OMEGA SOFTGEL