CYCLOGYL 2% EYE DROPS
FDA nonproprietary name: cyclopentolate hydrochloride
For 1 mL
Pharmacies pay
$14.63 – $22.10 filed
1 × $14.6264 to $22.096 per ML (the 2 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$11.85 filed
1 × $11.85366 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.54× – 0.81× estimated
Medicare paid between 0.54× and 0.81× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Cyclogyl” / “Cyclopentolate HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$21.82 – $30.42 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CYCLOGYL 2% EYE DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as cyclopentolate hydrochloride, under the trade name “Cyclogyl”.
FDA gives its dosage form as solution/ drops and its route as ophthalmic.
The labeler, the company named on the label, is Alcon Laboratories, Inc.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it in its brand rate-setting class B-ANDA, and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $14.63 – $22.10 for 1 mL, depending on the NDC ($14.6264 to $22.096 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 00065-0397-02 · Alcon Laboratories, Inc. · $22.096 per ML · eff. 2026-09-23 filed
- 00065-0397-05 · Alcon Laboratories, Inc. · $14.6264 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name cyclopentolate hydrochloride with CYCLOGYL 2% EYE DROPS.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CYCLOGYL 0.5% EYE DROPS | $6.40467 per ML filed | $11.85366 per ML filed |
| CYCLOGYL 2% EYE DROPS this page | $14.6264 to $22.096 per ML filed | $11.85366 per ML filed |
| CYCLOPENTOLATE 1% EYE DROP | $0.86977 per ML filed | $2.47663 per ML filed |
| CYCLOPENTOLATE 1% EYE DROPS | $0.86977 to $2.64533 per ML filed | $2.47663 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $11.85 for 1 mL, at an average of $11.85366 per ML in 2024 (2024-01-01 to 2024-12-31) for “Cyclogyl” and “Cyclopentolate HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 298 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $14.6264 to $22.096 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for CYCLOGYL 2% EYE DROPS labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Cyclogyl / Cyclopentolate HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (2 mL, 5 mL). So the card starts at 1 ML; change it to match your prescription.