CYRED EQ 28 DAY TABLET
FDA nonproprietary name: desogestrel and ethinyl estradiol
For 1 unit (EA)
Pharmacies pay
$0.14 filed
1 × $0.13531 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$0.31 filed
1 × $0.3134 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.3× estimated
Medicare paid 2.3× what pharmacies pay.
Part D averages every strength and form sold under “Cyred Eq” / “Desogestrel-Ethinyl Estradiol” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$5.16 estimated
$0.14 + $0.02 (15%) + $5.00 fee per fill = $5.16
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
CYRED EQ 28 DAY TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as desogestrel and ethinyl estradiol, under the trade name “Cyred EQ”.
FDA gives its dosage form as kit.
The labeler, the company named on the label, is Afaxys Pharma, LLC.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes); the FDA directory lists 1 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.14 for 1 unit (EA) (1 × $0.13531 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · NADAC explanation codes
All 2 NDCs
- 50102-0254-21 · not listed as a package in the FDA directory · $0.13531 per EA · eff. 2026-09-23 filed
- 50102-0254-23 · Afaxys Pharma, LLC · $0.13531 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
7 other products in the NADAC file share the FDA nonproprietary name desogestrel and ethinyl estradiol with CYRED EQ 28 DAY TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| APRI 28 DAY TABLET | $0.13531 per EA filed | $0.3707 per EA filed |
| CYRED EQ 28 DAY TABLET this page | $0.13531 per EA filed | $0.3134 per EA filed |
| ENSKYCE 28 TABLET | $0.13531 per EA filed | $0.37795 per EA filed |
| ISIBLOOM 28 DAY TABLET | $0.13531 per EA filed | $0.38436 per EA filed |
| JULEBER 28 DAY TABLET | $0.13531 per EA filed | $0.42398 per EA filed |
| RECLIPSEN 28 DAY TABLET | $0.13531 per EA filed | $0.45906 per EA filed |
| VELIVET 28 DAY TABLET | $0.53646 per EA filed | $0.84512 per EA filed |
| VOLNEA 0.15-0.02-0.01 MG TAB | $0.17245 per EA filed | $0.47882 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $0.31 for 1 unit (EA), at an average of $0.3134 per EA in 2024 (2024-01-01 to 2024-12-31) for “Cyred Eq” and “Desogestrel-Ethinyl Estradiol”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 43 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for CYRED EQ 28 DAY TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Cyred Eq / Desogestrel-Ethinyl Estradiol: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists 1 of its 2 NDCs (it does not list the other one) as dosage form “KIT” with no route. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. NADAC’s EA for it may be the whole kit or one item in it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.