DAPTOMYCIN 500 MG VIAL
For 1 unit (EA)
Pharmacies pay
$23.80 filed
1 × $23.79838 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$13.50 derived
1 × $13.50 per EA, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.57× estimated
Medicare pays 43% less than pharmacies pay.
14 labelers share HCPCS J0878 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$32.37 estimated
$23.80 + $3.57 (15%) + $5.00 fee per fill = $32.37
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DAPTOMYCIN 500 MG VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as daptomycin.
FDA gives its dosage form as injection, powder, lyophilized, for solution and its route as intravenous.
FDA lists 14 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Sagent Pharmaceuticals and Camber Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Lipopeptide Antibacterial.
The NADAC file of 2026-10-14 prices it under 21 NDCs (National Drug Codes); the FDA directory lists 20 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $23.80 for 1 unit (EA) (1 × $23.79838 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The 14 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Meitheal Pharmaceuticals Inc. | 3 | $23.79838 per EA filed |
| Hikma Pharmaceuticals USA Inc. | 2 | $23.79838 per EA filed |
| Mylan Institutional LLC | 2 | $23.79838 per EA filed |
| Sagent Pharmaceuticals | 2 | $23.79838 per EA filed |
| Xellia Pharmaceuticals USA LLC | 2 | $23.79838 per EA filed |
| APOTEX CORP. | 1 | $23.79838 per EA filed |
| BE Pharmaceuticals Inc. | 1 | $23.79838 per EA filed |
| Biocon Pharma Inc. | 1 | $23.79838 per EA filed |
| BluePoint Laboratories | 1 | $23.79838 per EA filed |
| Camber Pharmaceuticals, Inc. | 1 | $23.79838 per EA filed |
| Civica, Inc. | 1 | $23.79838 per EA filed |
| Dr.Reddy's Laboratories Inc., | 1 | $23.79838 per EA filed |
| Eugia US LLC | 1 | $23.79838 per EA filed |
| NorthStar RxLLC | 1 | $23.79838 per EA filed |
| Not listed as a package in the FDA directory | 1 | $23.79838 per EA filed |
All 21 NDCs, with labeler and price
- 00143-9444-01 · Hikma Pharmaceuticals USA Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 00143-9465-01 · Hikma Pharmaceuticals USA Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 25021-0174-15 · Sagent Pharmaceuticals · $23.79838 per EA · eff. 2026-09-23 filed
- 25021-0174-16 · Sagent Pharmaceuticals · $23.79838 per EA · eff. 2026-09-23 filed
- 31722-0102-10 · not listed as a package in the FDA directory · $23.79838 per EA · eff. 2026-09-23 filed
- 31722-0216-01 · Camber Pharmaceuticals, Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 43598-0413-11 · Dr.Reddy's Laboratories Inc., · $23.79838 per EA · eff. 2026-09-23 filed
- 55150-0344-01 · Eugia US LLC · $23.79838 per EA · eff. 2026-09-23 filed
- 60505-6229-04 · APOTEX CORP. · $23.79838 per EA · eff. 2026-09-23 filed
- 67457-0813-50 · Mylan Institutional LLC · $23.79838 per EA · eff. 2026-09-23 filed
- 67457-0941-15 · Mylan Institutional LLC · $23.79838 per EA · eff. 2026-09-23 filed
- 68001-0376-68 · BluePoint Laboratories · $23.79838 per EA · eff. 2026-09-23 filed
- 70377-0093-91 · Biocon Pharma Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 70594-0034-01 · Xellia Pharmaceuticals USA LLC · $23.79838 per EA · eff. 2026-09-23 filed
- 70594-0034-02 · Xellia Pharmaceuticals USA LLC · $23.79838 per EA · eff. 2026-09-23 filed
- 71288-0016-15 · Meitheal Pharmaceuticals Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 71288-0016-91 · Meitheal Pharmaceuticals Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 71288-0016-95 · Meitheal Pharmaceuticals Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 71839-0107-01 · BE Pharmaceuticals Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 72572-0102-01 · Civica, Inc. · $23.79838 per EA · eff. 2026-09-23 filed
- 72603-0152-01 · NorthStar RxLLC · $23.79838 per EA · eff. 2026-09-23 filed
What Medicare paid
Medicare Part B’s payment limit for HCPCS J0878, for 2026-10-01 to 2026-12-31, comes to $13.50 for 1 unit (EA), or $13.50 per EA once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0054 per 1 MG.
19 of the product’s 21 NDCs have this Medicare figure; the other 2 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists 20 of its 21 NDCs (it does not list the other one) as dosage form “INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION” with route “INTRAVENOUS”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.