OpenBilldrug price receipt

NADAC week of 2026-10-14

DEPO-PROVERA 150 MG/ML SYRINGE

FDA nonproprietary name: medroxyprogesterone acetate

For 1 mL

Pharmacies pay

$52.34 filed

1 × $52.335 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$56.81 filed

1 × $56.80944 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

1.1× estimated

Medicare paid 1.1× what pharmacies pay.

Part D averages every strength and form sold under “Depo-Provera” / “Medroxyprogesterone Acetate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$65.19 estimated

$52.34 + $7.85 (15%) + $5.00 fee per fill = $65.19

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

DEPO-PROVERA 150 MG/ML SYRINGE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as medroxyprogesterone acetate, under the trade name “Depo-Provera”.

FDA gives its dosage form as injection, suspension and its route as intramuscular.

The labeler, the company named on the label, is Pharmacia & Upjohn Company LLC.

FDA’s Established Pharmacologic Class for it is Progestin.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00009-7376-11.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $52.34 for 1 mL (1 × $52.335 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $27.36384 per ML filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

The NDC

Other strengths, forms and brands

6 other products in the NADAC file share the FDA nonproprietary name medroxyprogesterone acetate with DEPO-PROVERA 150 MG/ML SYRINGE.

ProductPharmacies pay per unitMedicare per unit
DEPO-PROVERA 150 MG/ML SYRINGE this page
brand · injection, suspension
$52.335 per ML filed
eff. 2026-09-23
$56.80944 per ML filed
Part D 2024 average
DEPO-PROVERA 150 MG/ML VIAL
brand · injection, suspension
$50.994 per ML filed
eff. 2026-04-22
$56.80944 per ML filed
Part D 2024 average
DEPO-SUBQ PROVERA 104 SYRINGE
brand · injection, suspension
$77.42965 per ML filed
eff. 2026-09-23
$83.04822 per ML filed
Part D 2024 average
MEDROXYPROGESTERONE 2.5 MG TAB
generic · tablet
$0.11556 per EA filed
eff. 2026-09-23
We don’t know yet
MEDROXYPROGESTERONE 5 MG TAB
generic · tablet
$0.14277 per EA filed
eff. 2026-09-23
We don’t know yet
MEDROXYPROGESTERONE 10 MG TAB
generic · tablet
$0.1523 per EA filed
eff. 2026-09-23
We don’t know yet
MEDROXYPROGESTERONE 150 MG/ML
generic · injection, suspension, extended release / injection, suspension
$18.85351 to $27.36384 per ML filed
eff. 2026-09-23
We don’t know yet

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

Its NADAC price is $52.335 per ML filed.

Of the 5 other products in FDA’s Progestin class priced per ML, 1 has a higher middle NADAC price and 4 a lower one. The one in the middle is MEDROXYPROGESTERONE 150 MG/ML, at $22.84953 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $56.81 for 1 mL, at an average of $56.80944 per ML in 2024 (2024-01-01 to 2024-12-31) for “Depo-Provera” and “Medroxyprogesterone Acetate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 178 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for DEPO-PROVERA 150 MG/ML SYRINGE labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Depo-Provera / Medroxyprogesterone Acetate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
Why does this page start at 1 mL?
NADAC prices this product per ML. The FDA NDC Directory’s package description gives 1 mL in one package for this product’s NDC (“1 SYRINGE in 1 CARTON (0009-7376-11) / 1 mL in 1 SYRINGE”), so the card starts at one package: 1 ML. Change it to match your prescription.