DOXEPIN 50 MG CAPSULE
For 30 capsules
Pharmacies pay
$4.71 filed
30 × $0.15714 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$27.67 filed
30 × $0.92245 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
5.9× estimated
Medicare paid 5.9× what pharmacies pay.
Part D averages every strength and form sold under “Doxepin HCl*” / “Doxepin HCl” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$10.42 estimated
$4.71 + $0.71 (15%) + $5.00 fee per fill = $10.42
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DOXEPIN 50 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as doxepin hydrochloride.
FDA gives its dosage form as capsule and its route as oral.
FDA lists 14 labelers (the companies named on the label) for its NDCs, among them Mylan Pharmaceuticals Inc., Major Pharmaceuticals and Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
FDA’s Established Pharmacologic Class for it is Tricyclic Antidepressant.
The NADAC file of 2026-10-14 prices it under 18 NDCs (National Drug Codes); the FDA directory lists 17 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.71 for 30 capsules (30 × $0.15714 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 capsules · NADAC explanation codes
The 14 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Ajanta Pharma USA Inc. | 2 | $0.15714 per EA filed |
| Mylan Pharmaceuticals Inc. | 2 | $0.15714 per EA filed |
| PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS | 2 | $0.15714 per EA filed |
| Alembic Pharmaceuticals Inc. | 1 | $0.15714 per EA filed |
| Amneal Pharmaceuticals LLC | 1 | $0.15714 per EA filed |
| Aurobindo Pharma Limited | 1 | $0.15714 per EA filed |
| Chartwell RX, LLC | 1 | $0.15714 per EA filed |
| Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 1 | $0.15714 per EA filed |
| Lifestar Pharma LLC | 1 | $0.15714 per EA filed |
| Major Pharmaceuticals | 1 | $0.15714 per EA filed |
| Mylan Institutional Inc. | 1 | $0.15714 per EA filed |
| NorthStar RxLLC | 1 | $0.15714 per EA filed |
| Novadoz Pharmaceuticals LLC | 1 | $0.15714 per EA filed |
| Rising Pharma Holdings, Inc. | 1 | $0.15714 per EA filed |
| Not listed as a package in the FDA directory | 1 | $0.15714 per EA filed |
All 18 NDCs, with labeler and price
- 00378-4250-01 · Mylan Pharmaceuticals Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 00378-4250-10 · Mylan Pharmaceuticals Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 00904-7054-61 · Major Pharmaceuticals · $0.15714 per EA · eff. 2026-09-23 filed
- 23155-0796-01 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 24658-0795-01 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.15714 per EA · eff. 2026-09-23 filed
- 24658-0795-10 · PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS · $0.15714 per EA · eff. 2026-09-23 filed
- 27241-0169-01 · Ajanta Pharma USA Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 27241-0169-10 · Ajanta Pharma USA Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 51079-0438-01 · not listed as a package in the FDA directory · $0.15714 per EA · eff. 2026-09-23 filed
- 51079-0438-20 · Mylan Institutional Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 59651-0175-01 · Aurobindo Pharma Limited · $0.15714 per EA · eff. 2026-09-23 filed
- 62135-0562-90 · Chartwell RX, LLC · $0.15714 per EA · eff. 2026-09-23 filed
- 62332-0645-31 · Alembic Pharmaceuticals Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 64980-0596-01 · Rising Pharma Holdings, Inc. · $0.15714 per EA · eff. 2026-09-23 filed
- 69238-1171-09 · Amneal Pharmaceuticals LLC · $0.15714 per EA · eff. 2026-09-23 filed
- 70756-0426-11 · Lifestar Pharma LLC · $0.15714 per EA · eff. 2026-09-23 filed
- 72205-0090-91 · Novadoz Pharmaceuticals LLC · $0.15714 per EA · eff. 2026-09-23 filed
- 72603-0392-01 · NorthStar RxLLC · $0.15714 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name doxepin hydrochloride with DOXEPIN 50 MG CAPSULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DOXEPIN 5% CREAM | $7.11754 per GM filed | We don’t know yet |
| DOXEPIN 10 MG CAPSULE | $0.07787 per EA filed | $0.92245 per EA filed |
| DOXEPIN 10 MG/ML ORAL CONC | $0.83884 per ML filed | We don’t know yet |
| DOXEPIN 25 MG CAPSULE | $0.14151 per EA filed | $0.92245 per EA filed |
| DOXEPIN 50 MG CAPSULE this page | $0.15714 per EA filed | $0.92245 per EA filed |
| DOXEPIN 75 MG CAPSULE | $0.19659 per EA filed | $0.92245 per EA filed |
| DOXEPIN 100 MG CAPSULE | $0.29013 per EA filed | $0.92245 per EA filed |
| DOXEPIN HCL 3 MG TABLET | $1.33336 per EA filed | $0.92245 per EA filed |
| DOXEPIN HCL 6 MG TABLET | $1.3716 per EA filed | $0.92245 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 18 NDCs’ NADAC prices is $0.15714 per EA filed.
Of the 34 other products in FDA’s Tricyclic Antidepressant class priced per EA, 20 have a higher middle NADAC price and 14 a lower one. The one in the middle is NORTRIPTYLINE HCL 50 MG CAP, at $0.20739 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $27.67 for 30 capsules, at an average of $0.92245 per EA in 2024 (2024-01-01 to 2024-12-31) for “Doxepin HCl*” and “Doxepin HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 1,270,415 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for DOXEPIN 50 MG CAPSULE labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Doxepin HCl* / Doxepin HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (106 of the 116 the name join matched); NDCs of another route or with no known FDA route do not. 4 of the 106 NDCs that point at this name are not listed in the FDA NDC Directory as packages of their own; their route was taken from FDA's record for the same product (labeler and product code). 112 of 116 NADAC NDCs joined to this name are priced per EA (3 per GM, 1 per ML): CMS's average mixes those units.
Related pages
Its pharmacologic class
Related in the same class
- AMITRIPTYLINE HCL 10 MG TAB
- NORTRIPTYLINE HCL 10 MG CAP
- IMIPRAMINE HCL 10 MG TABLET
- CLOMIPRAMINE 25 MG CAPSULE
- DESIPRAMINE 10 MG TABLET