DUPIXENT 200 MG/1.14 ML PEN
FDA nonproprietary name: dupilumab
For 2.28 mL
Pharmacies pay
$4,055.80 filed
2.28 × $1,778.85887 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$4,669.17 estimated
$4,055.80 + $608.37 (15%) + $5.00 fee per fill = $4,669.17
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
DUPIXENT 200 MG/1.14 ML PEN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as dupilumab, under the trade name “Dupixent”.
FDA gives its dosage form as injection, solution and its route as subcutaneous.
The labeler, the company named on the label, is Sanofi-Aventis U.S. LLC.
FDA’s Established Pharmacologic Class for it is Interleukin-4 Receptor alpha Antagonist.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00024-5919-02.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4,055.80 for 2.28 mL (2.28 × $1,778.85887 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 00024-5919-02 · Sanofi-Aventis U.S. LLC · $1,778.85887 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name dupilumab with DUPIXENT 200 MG/1.14 ML PEN.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| DUPIXENT 200 MG/1.14 ML PEN this page | $1,778.85887 per ML filed | We don’t know yet |
| DUPIXENT 200 MG/1.14 ML SYRING | $1,773.73509 per ML filed | We don’t know yet |
| DUPIXENT 300 MG/2 ML PEN | $1,009.5592 per ML filed | We don’t know yet |
| DUPIXENT 300 MG/2 ML SYRINGE | $1,010.59551 per ML filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
Its NADAC price is $1,778.85887 per ML filed.
Of the 3 other products in FDA’s Interleukin-4 Receptor alpha Antagonist class priced per ML, 0 have a higher middle NADAC price and 3 a lower one. The one in the middle is DUPIXENT 300 MG/2 ML SYRINGE, at $1,010.59551 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 2.28 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 2.28 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 2.28 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 2.28 mL in one package for this product’s NDC (“2 SYRINGE, GLASS in 1 CARTON (0024-5919-02) / 1.14 mL in 1 SYRINGE, GLASS (0024-5919-00)”), so the card starts at one package: 2.28 ML. Change it to match your prescription.