OpenBilldrug price receipt

NADAC week of 2026-10-14

EBGLYSS 250 MG/2 ML PEN

FDA nonproprietary name: lebrikizumab-lbkz

For 2 mL

Pharmacies pay

$3,567.05 filed

2 × $1,783.52375 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$3,434.52 filed

2 × $1,717.25781 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

0.96× estimated

Medicare paid about what pharmacies pay.

Part D averages every strength and form sold under “Ebglyss Pen” / “Lebrikizumab-Lbkz” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$4,107.11 estimated

$3,567.05 + $535.06 (15%) + $5.00 fee per fill = $4,107.11

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

EBGLYSS 250 MG/2 ML PEN is how the CMS NADAC file names this product. The FDA NDC Directory lists it as lebrikizumab-lbkz, under the trade name “EBGLYSS”.

FDA gives its dosage form as injection, solution and its route as subcutaneous.

The labeler, the company named on the label, is Eli Lilly and Company.

FDA’s Established Pharmacologic Class for it is Interleukin-13 Antagonist.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes); the FDA directory lists 1 of them.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $3,567.05 for 2 mL (2 × $1,783.52375 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

All 2 NDCs

What Medicare paid

Medicare Part D paid $3,434.52 for 2 mL, at an average of $1,717.25781 per ML in 2024 (2024-01-01 to 2024-12-31) for “Ebglyss Pen” and “Lebrikizumab-Lbkz”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 292 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for EBGLYSS 250 MG/2 ML PEN labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Ebglyss Pen / Lebrikizumab-Lbkz: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
Why does this page start at 2 mL?
NADAC prices this product per ML. The FDA NDC Directory’s package description gives 2 mL in one package for the 1 of this product’s 2 NDCs it lists (“1 SYRINGE in 1 CARTON (0002-7772-11) / 2 mL in 1 SYRINGE (0002-7772-01)”), so the card starts at one package: 2 ML. Change it to match your prescription.