FONDAPARINUX 2.5 MG/0.5 ML SYR
For 1 mL
Pharmacies pay
$12.12 – $22.16 filed
1 × $12.12467 to $22.16233 per ML (the 5 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$67.45 filed
1 × $67.44546 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
3.0× – 5.6× estimated
Medicare paid between 3.0× and 5.6× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Fondaparinux Sodium” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19, 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$18.94 – $30.48 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19, 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
FONDAPARINUX 2.5 MG/0.5 ML SYR is how the CMS NADAC file names this product. The FDA NDC Directory lists it as fondaparinux sodium.
FDA gives its dosage form as “injection” and “injection, solution” and its route as subcutaneous.
FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Sandoz Inc., Dr. Reddy's Laboratories Limited and Eugia US LLC.
FDA’s Established Pharmacologic Class for it is Factor Xa Inhibitor.
The NADAC file of 2026-10-14 prices it under 5 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $12.12 – $22.16 for 1 mL, depending on the NDC ($12.12467 to $22.16233 per ML), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-08-19 and 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 4, carried forward from the previous file; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
The NADAC of 4 of these 5 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-08-19. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
All 5 NDCs
- 00781-3443-95 · Sandoz Inc. · $22.16233 per ML · eff. 2026-08-19 filed carried forward
- 55111-0678-02 · Dr. Reddy's Laboratories Limited · $12.12467 per ML · eff. 2026-09-23 filed
- 55111-0678-10 · Dr. Reddy's Laboratories Limited · $22.16233 per ML · eff. 2026-08-19 filed carried forward
- 55150-0230-10 · Eugia US LLC · $22.16233 per ML · eff. 2026-08-19 filed carried forward
- 67457-0582-10 · Mylan Institutional LLC · $22.16233 per ML · eff. 2026-08-19 filed carried forward
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name fondaparinux sodium with FONDAPARINUX 2.5 MG/0.5 ML SYR.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FONDAPARINUX 2.5 MG/0.5 ML SYR this page | $12.12467 to $22.16233 per ML filed | $67.44546 per ML filed |
| FONDAPARINUX 7.5 MG/0.6 ML SYR | $42.80893 per ML filed | $67.44546 per ML filed |
| FONDAPARINUX 10 MG/0.8 ML SYR | $44.81613 per ML filed | $67.44546 per ML filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 5 NDCs’ NADAC prices is $22.16233 per ML filed.
Of the 4 other products in FDA’s Factor Xa Inhibitor class priced per ML, 2 have a higher middle NADAC price and 2 a lower one. The one in the middle is XARELTO 1 MG/ML SUSPENSION, at $3.77426 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $67.45 for 1 mL, at an average of $67.44546 per ML in 2024 (2024-01-01 to 2024-12-31) for “Fondaparinux Sodium”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 13,143 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $12.12467 to $22.16233 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for FONDAPARINUX 2.5 MG/0.5 ML SYR labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Fondaparinux Sodium / Fondaparinux Sodium: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (1 mL, 5 mL). So the card starts at 1 ML; change it to match your prescription.