GUANFACINE HCL ER 4 MG TABLET

What it is

GUANFACINE HCL ER 4 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as guanfacine, under the trade name “Guanfacine Extended-Release”.

FDA gives its dosage form as tablet, extended release and its route as oral.

FDA lists 8 labelers (the companies named on the label) for its NDCs, among them Actavis Pharma, Inc., Upsher-Smith Laboratories, LLC and Unichem Pharmaceuticals (USA), Inc.

FDA’s Established Pharmacologic Class for it is Central alpha-2 Adrenergic Agonist.

The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $5.29 for 30 tablets (30 × $0.17621 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · Why 30 tablets · NADAC explanation codes

The 8 labelers

Other strengths, forms and brands

9 other products in the NADAC file share the FDA nonproprietary name guanfacine with GUANFACINE HCL ER 4 MG TABLET.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 8 NDCs’ NADAC prices is $0.17621 per EA filed.

Of the 22 other products in FDA’s Central alpha-2 Adrenergic Agonist class priced per EA, 10 have a higher middle NADAC price and 12 a lower one. The one in the middle is GUANFACINE HCL ER 2 MG TABLET, at $0.14767 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $25.20 for 30 tablets, at an average of $0.83991 per EA in 2024 (2024-01-01 to 2024-12-31) for “Guanfacine HCl ER” and “Guanfacine HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 134,577 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.