GVOKE HYPOPEN 2-PK 1 MG/0.2 ML
FDA nonproprietary name: glucagon injection, solution
For 0.4 mL
Pharmacies pay
$638.48 filed
0.4 × $1,596.19346 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$739.25 estimated
$638.48 + $95.77 (15%) + $5.00 fee per fill = $739.25
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
GVOKE HYPOPEN 2-PK 1 MG/0.2 ML is how the CMS NADAC file names this product. The FDA NDC Directory lists it as glucagon injection, solution, under the trade name “Gvoke HypoPen 1 mg Auto-Injector”.
FDA gives its dosage form as injection, solution and its route as subcutaneous.
The labeler, the company named on the label, is Xeris Pharmaceuticals, Inc.
FDA lists it under 2 Established Pharmacologic Classes: Antihypoglycemic Agent and Gastrointestinal Motility Inhibitor.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 72065-0121-12.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $638.48 for 0.4 mL (0.4 × $1,596.19346 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The NDC
- 72065-0121-12 · Xeris Pharmaceuticals, Inc. · $1,596.19346 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name glucagon injection, solution with GVOKE HYPOPEN 2-PK 1 MG/0.2 ML.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| GVOKE 1 MG/0.2 ML KIT | $1,600.98636 per ML filed | $1,525.1287 per ML filed |
| GVOKE HYPOPEN 1-PK 1 MG/0.2 ML | $1,603.18226 per ML filed | We don’t know yet |
| GVOKE HYPOPEN 2-PK 1 MG/0.2 ML this page | $1,596.19346 per ML filed | We don’t know yet |
| GVOKE HYPOPEN 2PK 0.5 MG/0.1 ML | $3,202.32985 per ML filed | We don’t know yet |
| GVOKE PFS 1-PK 1 MG/0.2 ML SYR | $1,600.95652 per ML filed | We don’t know yet |
| GVOKE PFS 2-PK 1 MG/0.2 ML SYR | $1,604.33929 per ML filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $1,596.19346 per ML filed.
Of the 7 other products in FDA’s Antihypoglycemic Agent class priced per ML, 5 have a higher middle NADAC price and 2 a lower one. The one in the middle is GVOKE 1 MG/0.2 ML KIT, at $1,600.98636 per ML filed (eff. 2026-09-23).
Of the 5 other products in FDA’s Gastrointestinal Motility Inhibitor class priced per ML, 5 have a higher middle NADAC price and 0 a lower one. The one in the middle is GVOKE HYPOPEN 1-PK 1 MG/0.2 ML, at $1,603.18226 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 0.4 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 0.4 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 0.4 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 0.4 mL in one package for this product’s NDC (“2 POUCH in 1 CARTON (72065-121-12) / 1 SYRINGE, PLASTIC in 1 POUCH / .2 mL in 1 SYRINGE, PLASTIC”), so the card starts at one package: 0.4 ML. Change it to match your prescription.