GYNAZOLE 1 2% CREAM

What it is

GYNAZOLE 1 2% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as butoconazole nitrate, under the trade name “gynazole 1”.

FDA gives its dosage form as cream and its route as vaginal.

The labeler, the company named on the label, is Padagis Israel Pharmaceuticals Ltd.

FDA’s Established Pharmacologic Class for it is Azole Antifungal.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 45802-0396-01.

NADAC classes it in its brand rate-setting class B-ANDA, and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $135.16 for 5.8 g (5.8 × $23.30382 per GM, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

The NDC

• 45802-0396-01 · Padagis Israel Pharmaceuticals Ltd · $23.30382 per GM · eff. 2026-09-23 filed

Compared with its class

Its NADAC price is $23.30382 per GM filed.

Of the 36 other products in FDA’s Azole Antifungal class priced per GM, 0 have a higher middle NADAC price and 36 a lower one. The one in the middle is FT ANTIFUNGAL 2% TOPICAL CREAM, at $0.12071 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $140.60 for 5.8 g, at an average of $24.2418 per GM in 2024 (2024-01-01 to 2024-12-31) for “Gynazole 1” and “Butoconazole Nitrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 249 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 5.8 g? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 5.8 g; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.