HYDROXOCOBALAMIN 1,000 MCG/ML
For 30 mL
Pharmacies pay
$24.43 filed
30 × $0.8144 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-03-18 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$21.00 derived
30 × $0.70 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.86× derived
Medicare pays 14% less than pharmacies pay.
Derived because only one labeler, Actavis Pharma, Inc., is listed for HCPCS J3425 on the CMS crosswalk, so the payment limit comes from that company’s own products under the code, not an average across companies.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-03-18 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$33.09 estimated
$24.43 + $3.66 (15%) + $5.00 fee per fill = $33.09
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-03-18 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
HYDROXOCOBALAMIN 1,000 MCG/ML is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hydroxocobalamin.
FDA gives its dosage form as injection, solution and its route as intramuscular.
The labeler, the company named on the label, is Actavis Pharma, Inc.
FDA’s Established Pharmacologic Class for it is Antidote.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 00591-2888-30.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $24.43 for 30 mL (30 × $0.8144 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-03-18. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-03-18. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
The NDC
- 00591-2888-30 · Actavis Pharma, Inc. · $0.8144 per ML · eff. 2026-03-18 filed carried forward
What Medicare paid
Medicare Part B’s payment limit for HCPCS J3425, for 2026-10-01 to 2026-12-31, comes to $21.00 for 30 mL, or $0.70 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0014 per 10 MCG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 30 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 30 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 30 mL in one package for this product’s NDC (“1 VIAL, MULTI-DOSE in 1 CARTON (0591-2888-30) / 30 mL in 1 VIAL, MULTI-DOSE”), so the card starts at one package: 30 ML. Change it to match your prescription.