HYLENEX 150 UNITS/ML VIAL

What it is

HYLENEX 150 UNITS/ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hyaluronidase, under the trade name “HYLENEX Recombinant”.

FDA gives its dosage form as injection, solution and its route as subcutaneous.

The labeler, the company named on the label, is Antares Pharma, Inc.

FDA’s Established Pharmacologic Class for it is Endoglycosidase.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 18657-0117-04.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $214.75 for 4 mL (4 × $53.68773 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

What NADAC measures · NADAC explanation codes

The NDC

• 18657-0117-04 · Antares Pharma, Inc. · $53.68773 per ML · eff. 2026-09-23 filed

What Medicare paid

Medicare Part B’s payment limit for HCPCS J3473, for 2026-10-01 to 2026-12-31, comes to $218.40 for 4 mL, or $54.60 per ML once converted to NADAC’s unit for this product.

Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.

The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0728 per 1 USP UNIT.

Medicare's price is not your price.

What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 4 mL? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 4 mL; your package may hold a different amount.
• If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.