HYOSCYAMINE SULF 0.125 MG TAB
For 30 tablets
Pharmacies pay
$4.38 filed
30 × $0.14589 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$11.43 filed
30 × $0.3811 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.6× estimated
Medicare paid 2.6× what pharmacies pay.
Part D averages every strength and form sold under “Hyoscyamine Sulfate*” / “Hyoscyamine Sulfate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$10.04 estimated
$4.38 + $0.66 (15%) + $5.00 fee per fill = $10.04
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
HYOSCYAMINE SULF 0.125 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as hyoscyamine sulfate, under the trade name “Hyoscyamine Sulfate TAB”.
FDA gives its dosage form as tablet and its route as oral.
Its labelers, the companies named on the label, are Acella Pharmaceuticals, LLC, Chartwell RX, LLC and ANI Pharmaceuticals, Inc.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $4.38 for 30 tablets (30 × $0.14589 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 3 NDCs
- 42192-0340-01 · Acella Pharmaceuticals, LLC · $0.14589 per EA · eff. 2026-09-23 filed
- 62135-0512-12 · Chartwell RX, LLC · $0.14589 per EA · eff. 2026-09-23 filed
- 62559-0421-01 · ANI Pharmaceuticals, Inc. · $0.14589 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share the FDA nonproprietary name hyoscyamine sulfate with HYOSCYAMINE SULF 0.125 MG TAB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| HYOSCYAMINE 0.125 MG ODT | $0.14421 per EA filed | We don’t know yet |
| HYOSCYAMINE 0.125 MG TAB SL | $0.17066 per EA filed | $0.3811 per EA filed |
| HYOSCYAMINE ER 0.375 MG TAB | $0.53556 per EA filed | $0.54794 per EA filed |
| HYOSCYAMINE SULF 0.125 MG TAB this page | $0.14589 per EA filed | $0.3811 per EA filed |
| LEVSIN 0.125 MG TABLET | $2.65588 per EA filed | $2.67098 per EA filed |
| LEVSIN-SL 0.125 MG TABLET SL | $2.7044 per EA filed | $2.31603 per EA filed |
| NULEV 0.125 MG CHEWABLE MELT | $0.14421 per EA filed | We don’t know yet |
| OSCIMIN 0.125 MG TABLET | $0.14589 per EA filed | $0.25257 per EA filed |
| OSCIMIN SL 0.125 MG TABLET | $0.17066 per EA filed | We don’t know yet |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $11.43 for 30 tablets, at an average of $0.3811 per EA in 2024 (2024-01-01 to 2024-12-31) for “Hyoscyamine Sulfate*” and “Hyoscyamine Sulfate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 24,235 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for HYOSCYAMINE SULF 0.125 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Hyoscyamine Sulfate* / Hyoscyamine Sulfate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. Only NADAC NDCs whose FDA route includes ORAL point at this name (5 of the 7 the name join matched); NDCs of another route or with no known FDA route do not.