HYZAAR 100-12.5 TABLET

What it is

HYZAAR 100-12.5 TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as losartan potassium and hydrochlorothiazide, under the trade name “HYZAAR”.

FDA gives its dosage form as tablet, film coated and its route as oral.

The labeler, the company named on the label, is Organon LLC.

FDA lists it under 2 Established Pharmacologic Classes: Angiotensin 2 Receptor Blocker and Thiazide Diuretic.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $204.60 for 30 tablets (30 × $6.81999 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-01. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 4, carried forward from the previous file.

The NADAC of all 2 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-01-01. The file is new; the price is not.

NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $0.07619 per EA filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What NADAC measures · Why 30 tablets · NADAC explanation codes · Carried-forward prices

All 2 NDCs

• 78206-0140-01 · Organon LLC · $6.81999 per EA · eff. 2026-01-01 filed carried forward
• 78206-0140-02 · Organon LLC · $6.81999 per EA · eff. 2026-01-01 filed carried forward

Other strengths, forms and brands

5 other products in the NADAC file share the FDA nonproprietary name losartan potassium and hydrochlorothiazide with HYZAAR 100-12.5 TABLET.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $6.81999 per EA filed.

Of the 107 other products in FDA’s Angiotensin 2 Receptor Blocker class priced per EA, 33 have a higher middle NADAC price and 74 a lower one. The one in the middle is CANDESARTAN-HYDROCHLOROTHIAZIDE 32-25 MG TAB, at $1.07781 per EA filed (eff. 2026-09-23).

Of the 68 other products in FDA’s Thiazide Diuretic class priced per EA, 8 have a higher middle NADAC price and 60 a lower one. The one in the middle is TELMISARTAN-HYDROCHLOROTHIAZIDE 40-12.5 MG TB, at $0.3567 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $164.99 for 30 tablets, at an average of $5.49976 per EA in 2024 (2024-01-01 to 2024-12-31) for “Hyzaar” and “Losartan/Hydrochlorothiazide”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 3,947 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.