ISOSORBIDE DINITRATE 5 MG TAB
For 30 tablets
Pharmacies pay
$5.30 filed
30 × $0.17675 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$14.34 filed
30 × $0.47798 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
2.7× estimated
Medicare paid 2.7× what pharmacies pay.
Part D averages every strength and form sold under “Isosorbide Dinitrate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$11.10 estimated
$5.30 + $0.80 (15%) + $5.00 fee per fill = $11.10
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ISOSORBIDE DINITRATE 5 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as isosorbide dinitrate, under the trade name “Isosorbide”.
FDA gives its dosage form as tablet and its route as oral.
FDA lists 8 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Sandoz Inc. and Northstar Rx LLC.
FDA’s Established Pharmacologic Class for it is Nitrate Vasodilator.
The NADAC file of 2026-10-14 prices it under 13 NDCs (National Drug Codes); the FDA directory lists 12 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $5.30 for 30 tablets (30 × $0.17675 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 8 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Advagen Pharma Ltd | 2 | $0.17675 per EA filed |
| Hikma Pharmaceuticals USA Inc. | 2 | $0.17675 per EA filed |
| Par Health USA, LLC | 2 | $0.17675 per EA filed |
| Sandoz Inc. | 2 | $0.17675 per EA filed |
| AvPAK | 1 | $0.17675 per EA filed |
| BluePoint Laboratories | 1 | $0.17675 per EA filed |
| Northstar Rx LLC | 1 | $0.17675 per EA filed |
| Zydus Pharmaceuticals (USA) Inc. | 1 | $0.17675 per EA filed |
| Not listed as a package in the FDA directory | 1 | $0.17675 per EA filed |
All 13 NDCs, with labeler and price
- 00143-1769-01 · Hikma Pharmaceuticals USA Inc. · $0.17675 per EA · eff. 2026-09-23 filed
- 00143-1769-10 · Hikma Pharmaceuticals USA Inc. · $0.17675 per EA · eff. 2026-09-23 filed
- 00781-1635-01 · Sandoz Inc. · $0.17675 per EA · eff. 2026-09-23 filed
- 00781-1635-10 · Sandoz Inc. · $0.17675 per EA · eff. 2026-09-23 filed
- 16714-0007-01 · Northstar Rx LLC · $0.17675 per EA · eff. 2026-09-23 filed
- 49884-0020-01 · Par Health USA, LLC · $0.17675 per EA · eff. 2026-09-23 filed
- 49884-0020-10 · Par Health USA, LLC · $0.17675 per EA · eff. 2026-09-23 filed
- 50268-0447-11 · not listed as a package in the FDA directory · $0.17675 per EA · eff. 2026-09-23 filed
- 50268-0447-15 · AvPAK · $0.17675 per EA · eff. 2026-09-23 filed
- 68001-0373-00 · BluePoint Laboratories · $0.17675 per EA · eff. 2026-09-23 filed
- 70710-1148-01 · Zydus Pharmaceuticals (USA) Inc. · $0.17675 per EA · eff. 2026-09-23 filed
- 72888-0081-00 · Advagen Pharma Ltd · $0.17675 per EA · eff. 2026-09-23 filed
- 72888-0081-01 · Advagen Pharma Ltd · $0.17675 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
4 other products in the NADAC file share the FDA nonproprietary name isosorbide dinitrate with ISOSORBIDE DINITRATE 5 MG TAB.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ISOSORBIDE DINITRATE 5 MG TAB this page | $0.17675 per EA filed | $0.47798 per EA filed |
| ISOSORBIDE DINITRATE 10 MG TAB | $0.15421 per EA filed | $0.47798 per EA filed |
| ISOSORBIDE DINITRATE 20 MG TAB | $0.19894 per EA filed | $0.47798 per EA filed |
| ISOSORBIDE DINITRATE 30 MG TAB | $0.2808 per EA filed | $0.47798 per EA filed |
| ISOSORBIDE DINITRATE 40 MG TAB | $3.3103 per EA filed | $0.47798 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 13 NDCs’ NADAC prices is $0.17675 per EA filed.
Of the 19 other products in FDA’s Nitrate Vasodilator class priced per EA, 12 have a higher middle NADAC price and 7 a lower one. The one in the middle is NITROGLYCERIN 0.1 MG/HR PATCH, at $0.49331 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $14.34 for 30 tablets, at an average of $0.47798 per EA in 2024 (2024-01-01 to 2024-12-31) for “Isosorbide Dinitrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 539,423 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for ISOSORBIDE DINITRATE 5 MG TAB labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Isosorbide Dinitrate / Isosorbide Dinitrate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.