KEPPRA XR 500 MG TABLET
FDA nonproprietary name: levetiracetam
For 30 tablets
Pharmacies pay
$270.73 filed
30 × $9.0242 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$311.25 filed
30 × $10.37505 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.1× estimated
Medicare paid 1.1× what pharmacies pay.
Part D averages every strength and form sold under “Keppra XR” / “Levetiracetam” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$316.34 estimated
$270.73 + $40.61 (15%) + $5.00 fee per fill = $316.34
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
KEPPRA XR 500 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as levetiracetam, under the trade name “Keppra XR”.
FDA gives its dosage form as tablet, film coated, extended release and its route as oral.
The labeler, the company named on the label, is UCB, Inc.
FDA lists no Established Pharmacologic Class for it.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 50474-0598-66.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $270.73 for 30 tablets (30 × $9.0242 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.17377 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 tablets · NADAC explanation codes
The NDC
- 50474-0598-66 · UCB, Inc. · $9.0242 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
17 other products in the NADAC file share the FDA nonproprietary name levetiracetam with KEPPRA XR 500 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| KEPPRA 1,000 MG TABLET | $19.8712 per EA filed | We don’t know yet |
| KEPPRA 100 MG/ML ORAL SOLN | $1.91893 per ML filed | We don’t know yet |
| KEPPRA 250 MG TABLET | $8.07857 per EA filed | We don’t know yet |
| KEPPRA 500 MG TABLET | $9.91702 per EA filed | We don’t know yet |
| KEPPRA 750 MG TABLET | $13.46136 per EA filed | We don’t know yet |
| KEPPRA XR 500 MG TABLET this page | $9.0242 per EA filed | $10.37505 per EA filed |
| KEPPRA XR 750 MG TABLET | $13.48131 per EA filed | $10.37505 per EA filed |
| LEVETIRACETAM 1,000 MG TABLET | $0.15968 per EA filed | $0.26202 per EA filed |
| LEVETIRACETAM 100 MG/ML SOLN | $0.03015 per ML filed | We don’t know yet |
| LEVETIRACETAM 250 MG TABLET | $0.05618 per EA filed | $0.26202 per EA filed |
| LEVETIRACETAM 500 MG TABLET | $0.07362 per EA filed | $0.26202 per EA filed |
| LEVETIRACETAM 750 MG TABLET | $0.10924 per EA filed | $0.26202 per EA filed |
| LEVETIRACETAM ER 500 MG TABLET | $0.17377 per EA filed | $0.52537 per EA filed |
| LEVETIRACETAM ER 750 MG TABLET | $0.22338 per EA filed | $0.52537 per EA filed |
| ROWEEPRA 500 MG TABLET | $0.07362 per EA filed | We don’t know yet |
| SPRITAM 1,000 MG TABLET | $10.199 per EA filed | $10.47293 per EA filed |
| SPRITAM 250 MG TABLET | $10.27223 per EA filed | $10.47293 per EA filed |
| SPRITAM 500 MG TABLET | $10.2412 per EA filed | $10.47293 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. between 2025-12-17 and 2026-09-23 (4 dates) · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $311.25 for 30 tablets, at an average of $10.37505 per EA in 2024 (2024-01-01 to 2024-12-31) for “Keppra XR” and “Levetiracetam”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 13,615 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: LEVETIRACETAM ER 500 MG TABLET. Ask your pharmacist or prescriber; do not switch on your own.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for KEPPRA XR 500 MG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Keppra XR / Levetiracetam: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name.