OpenBilldrug price receipt

NADAC week of 2026-10-14

LEUCOVORIN CALCIUM 25 MG TAB

For 30 tablets

Pharmacies pay

$48.14 filed

30 × $1.60475 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$69.52 filed

30 × $2.31748 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

1.4× estimated

Medicare paid 1.4× what pharmacies pay.

Part D averages every strength and form sold under “Leucovorin Calcium*” / “Leucovorin Calcium” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$60.36 estimated

$48.14 + $7.22 (15%) + $5.00 fee per fill = $60.36

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

LEUCOVORIN CALCIUM 25 MG TAB is how the CMS NADAC file names this product. The FDA NDC Directory lists it as leucovorin calcium.

FDA gives its dosage form as tablet and its route as oral.

FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Hikma Pharmaceuticals USA Inc., Teva Pharmaceuticals USA, Inc. and Major Pharmaceuticals.

FDA’s Established Pharmacologic Class for it is Folate Analog.

The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes); the FDA directory lists 7 of them.

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $48.14 for 30 tablets (30 × $1.60475 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

The 7 labelers

LabelerNDCsPharmacies pay per unit
American Health Packaging1$1.60475 per EA filed
Epic Pharma LLC1$1.60475 per EA filed
Hikma Pharmaceuticals USA Inc.1$1.60475 per EA filed
Ingenus Pharmaceuticals, LLC1$1.60475 per EA filed
Leading Pharma, LLC1$1.60475 per EA filed
Major Pharmaceuticals1$1.60475 per EA filed
Teva Pharmaceuticals USA, Inc.1$1.60475 per EA filed
Not listed as a package in the FDA directory1$1.60475 per EA filed
All 8 NDCs, with labeler and price
  • 00054-4499-11 · Hikma Pharmaceuticals USA Inc. · $1.60475 per EA · eff. 2026-09-23 filed
  • 00555-0485-27 · Teva Pharmaceuticals USA, Inc. · $1.60475 per EA · eff. 2026-09-23 filed
  • 00904-7584-10 · Major Pharmaceuticals · $1.60475 per EA · eff. 2026-09-23 filed
  • 42806-0359-25 · Epic Pharma LLC · $1.60475 per EA · eff. 2026-09-23 filed
  • 50742-0184-25 · Ingenus Pharmaceuticals, LLC · $1.60475 per EA · eff. 2026-09-23 filed
  • 60687-0227-11 · not listed as a package in the FDA directory · $1.60475 per EA · eff. 2026-09-23 filed
  • 60687-0227-94 · American Health Packaging · $1.60475 per EA · eff. 2026-09-23 filed
  • 69315-0187-25 · Leading Pharma, LLC · $1.60475 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

3 other products in the NADAC file share the FDA nonproprietary name leucovorin calcium with LEUCOVORIN CALCIUM 25 MG TAB.

ProductPharmacies pay per unitMedicare per unit
LEUCOVORIN CALCIUM 5 MG TAB
generic · tablet
$0.33003 per EA filed
eff. 2026-09-23
$2.31748 per EA filed
Part D 2024 average
LEUCOVORIN CALCIUM 10 MG TAB
generic · tablet
$2.07783 per EA filed
eff. 2026-09-23
$2.31748 per EA filed
Part D 2024 average
LEUCOVORIN CALCIUM 15 MG TAB
generic · tablet
$1.58667 per EA filed
eff. 2026-09-23
$2.31748 per EA filed
Part D 2024 average
LEUCOVORIN CALCIUM 25 MG TAB this page
generic · tablet
$1.60475 per EA filed
eff. 2026-09-23
$2.31748 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 8 NDCs’ NADAC prices is $1.60475 per EA filed.

Of the 9 other products in FDA’s Folate Analog class priced per EA, 7 have a higher middle NADAC price and 2 a lower one. The one in the middle is VITAFOL ULTRA SOFTGEL, at $4.52255 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $69.52 for 30 tablets, at an average of $2.31748 per EA in 2024 (2024-01-01 to 2024-12-31) for “Leucovorin Calcium*” and “Leucovorin Calcium”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 104,039 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for LEUCOVORIN CALCIUM 25 MG TAB labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Leucovorin Calcium* / Leucovorin Calcium: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. All 31 NADAC NDCs the name join matched to it have an FDA route including ORAL. 1 of the 31 NDCs that point at this name is not listed in the FDA NDC Directory as a package of its own; its route was taken from FDA's record for the same product (labeler and product code).