OpenBilldrug price receipt

NADAC week of 2026-10-14

LOHIST-DM SYRUP

FDA nonproprietary name: brompheniramine maleate, dextromethorphan hydrobromide and phenylephrine hydrochloride

For 473 mL

Pharmacies pay

$35.04 filed

473 × $0.07408 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.


The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$45.30 estimated

$35.04 + $5.26 (15%) + $5.00 fee per fill = $45.30

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

LOHIST-DM SYRUP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as brompheniramine maleate, dextromethorphan hydrobromide and phenylephrine hydrochloride, under the trade name “LoHist DM”.

FDA gives its dosage form as liquid and its route as oral.

The labeler, the company named on the label, is Larken Laboratories, Inc.

FDA lists it under 3 Established Pharmacologic Classes: alpha-1 Adrenergic Agonist, Sigma-1 Agonist and Uncompetitive N-methyl-D-aspartate Receptor Antagonist.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 68047-0129-16.

NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.

What pharmacies pay

Pharmacies pay $35.04 for 473 mL (473 × $0.07408 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

The NDC

Other strengths, forms and brands

1 other product in the NADAC file shares the FDA nonproprietary name brompheniramine maleate, dextromethorphan hydrobromide and phenylephrine hydrochloride with LOHIST-DM SYRUP.

ProductPharmacies pay per unitMedicare per unit
ENDACOF-DM LIQUID
generic · liquid
$0.05121 per ML filed
eff. 2026-09-23
We don’t know yet
LOHIST-DM SYRUP this page
generic · liquid
$0.07408 per ML filed
eff. 2026-09-23
We don’t know yet

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Compared with its class

Its NADAC price is $0.07408 per ML filed.

Of the 30 other products in FDA’s alpha-1 Adrenergic Agonist class priced per ML, 8 have a higher middle NADAC price and 22 a lower one. The one in the middle is RYNEX DM LIQUID, at $0.05121 per ML filed (eff. 2026-09-23).

Of the 63 other products in FDA’s Sigma-1 Agonist class priced per ML, 6 have a higher middle NADAC price and 57 a lower one. The one in the middle is GNP TUSSIN LONG-ACTING LIQUID, at $0.02263 per ML filed (eff. 2026-09-23).

Of the 63 other products in FDA’s Uncompetitive N-methyl-D-aspartate Receptor Antagonist class priced per ML, 6 have a higher middle NADAC price and 57 a lower one. The one in the middle is GNP TUSSIN LONG-ACTING LIQUID, at $0.02263 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

We don’t know yet; the card above says why.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why does this page start at 473 mL?
NADAC prices this product per ML. The FDA NDC Directory’s package description gives 473 mL in one package for this product’s NDC (“473 mL in 1 BOTTLE (68047-129-16)”), so the card starts at one package: 473 ML. Change it to match your prescription.