METHYLIN 5 MG/5 ML SOLUTION
FDA nonproprietary name: methylphenidate hydrochloride
For 500 mL
Pharmacies pay
$80.81 filed
500 × $0.16161 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: The Part D file flags this drug’s average spending per dosage unit as an outlier, so OpenBill does not use it as a reference price. Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$97.93 estimated
$80.81 + $12.12 (15%) + $5.00 fee per fill = $97.93
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
METHYLIN 5 MG/5 ML SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as methylphenidate hydrochloride, under the trade name “Methylin”.
FDA gives its dosage form as solution and its route as oral.
The labeler, the company named on the label, is SHIONOGI INC.
FDA’s Established Pharmacologic Class for it is Central Nervous System Stimulant.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 59630-0750-50.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $80.81 for 500 mL (500 × $0.16161 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $0.07817 per ML filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · NADAC explanation codes
The NDC
- 59630-0750-50 · SHIONOGI INC. · $0.16161 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
59 other products in the NADAC file share the FDA nonproprietary name methylphenidate hydrochloride with METHYLIN 5 MG/5 ML SOLUTION. The 23 below share a strength or dosage form with it first; search OpenBill for the rest.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CONCERTA ER 18 MG TABLET | $12.32528 per EA filed | We don’t know yet |
| CONCERTA ER 27 MG TABLET | $12.65426 per EA filed | We don’t know yet |
| CONCERTA ER 36 MG TABLET | $13.04275 per EA filed | We don’t know yet |
| CONCERTA ER 54 MG TABLET | $14.17967 per EA filed | We don’t know yet |
| JORNAY PM 20 MG CAPSULE | $15.39302 per EA filed | $15.06416 per EA filed |
| JORNAY PM 40 MG CAPSULE | $15.40511 per EA filed | $15.06416 per EA filed |
| JORNAY PM 60 MG CAPSULE | $15.40191 per EA filed | $15.06416 per EA filed |
| JORNAY PM 80 MG CAPSULE | $15.40151 per EA filed | $15.06416 per EA filed |
| JORNAY PM 100 MG CAPSULE | $15.39596 per EA filed | $15.06416 per EA filed |
| METHYLIN 5 MG/5 ML SOLUTION this page | $0.16161 per ML filed | We don’t know yet |
| METHYLIN 10 MG/5 ML SOLUTION | $0.23086 per ML filed | We don’t know yet |
| METHYLPHENIDATE 2.5 MG CHEW TB | $1.29914 per EA filed | We don’t know yet |
| METHYLPHENIDATE 5 MG CHEW TAB | $2.00923 per EA filed | We don’t know yet |
| METHYLPHENIDATE 5 MG TABLET | $0.12682 per EA filed | We don’t know yet |
| METHYLPHENIDATE 5 MG/5 ML SOLN | $0.07817 per ML filed | We don’t know yet |
| METHYLPHENIDATE 10 MG CHEW TAB | $2.95383 per EA filed | We don’t know yet |
| METHYLPHENIDATE 10 MG TABLET | $0.15796 per EA filed | We don’t know yet |
| METHYLPHENIDATE 10 MG/5 ML SOL | $0.1199 per ML filed | We don’t know yet |
| METHYLPHENIDATE 20 MG TABLET | $0.20139 per EA filed | We don’t know yet |
| METHYLPHENIDATE CD 10 MG CAP | $1.40098 per EA filed | $2.4095 per EA filed |
| METHYLPHENIDATE CD 20 MG CAP | $1.38759 per EA filed | $2.4095 per EA filed |
| METHYLPHENIDATE CD 30 MG CAP | $1.79463 per EA filed | $2.4095 per EA filed |
| METHYLPHENIDATE CD 40 MG CAP | $1.44136 per EA filed | $2.4095 per EA filed |
| METHYLPHENIDATE CD 50 MG CAP | $1.57263 per EA filed | $2.4095 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $0.16161 per ML filed.
Of the 7 other products in FDA’s Central Nervous System Stimulant class priced per ML, 5 have a higher middle NADAC price and 2 a lower one. The one in the middle is DEXTROAMPHETAMINE 5 MG/5 ML, at $1.14342 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 500 mL? Is it lower than what I would pay through my insurance?
- Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: METHYLPHENIDATE 5 MG/5 ML SOLN. Ask your pharmacist or prescriber; do not switch on your own.
- How much is in the package I am getting? This page uses 500 mL; your package may hold a different amount.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 500 mL?
- NADAC prices this product per ML. The FDA NDC Directory’s package description gives 500 mL in one package for this product’s NDC (“500 mL in 1 BOTTLE (59630-750-50)”), so the card starts at one package: 500 ML. Change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- VYVANSE 10 MG CAPSULE
- BUTALBITAL-ASPIRIN-CAFFEINE 50-325-40 MG CAPSULE
- DEXMETHYLPHENIDATE ER 10 MG CP
- ADDERALL XR 10 MG CAPSULE
- ASCOMP WITH CODEINE CAPSULE