MISOPROSTOL 200 MCG TABLET
For 30 tablets
Pharmacies pay
$21.57 filed
30 × $0.71894 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$20.12 filed
30 × $0.67069 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.93× estimated
Medicare paid 7% less than pharmacies pay.
Part D averages every strength and form sold under “Misoprostol” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$29.81 estimated
$21.57 + $3.24 (15%) + $5.00 fee per fill = $29.81
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
MISOPROSTOL 200 MCG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as misoprostol.
FDA gives its dosage form as tablet and its route as oral.
FDA lists 5 labelers (the companies named on the label) for its NDCs, among them GenBioPro, Inc., AvPAK and Mylan Pharmaceuticals Inc.
FDA’s Established Pharmacologic Class for it is Prostaglandin E1 Analog.
The NADAC file of 2026-10-14 prices it under 11 NDCs (National Drug Codes); the FDA directory lists 9 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $21.57 for 30 tablets (30 × $0.71894 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 5 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| GenBioPro, Inc. | 3 | $0.71894 per EA filed |
| ANI Pharmaceuticals, Inc. | 2 | $0.71894 per EA filed |
| Mylan Pharmaceuticals Inc. | 2 | $0.71894 per EA filed |
| American Health Packaging | 1 | $0.71894 per EA filed |
| AvPAK | 1 | $0.71894 per EA filed |
| Not listed as a package in the FDA directory | 2 | $0.71894 per EA filed |
All 11 NDCs, with labeler and price
- 43393-0024-04 · GenBioPro, Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 43393-0200-04 · not listed as a package in the FDA directory · $0.71894 per EA · eff. 2026-09-23 filed
- 43393-0200-48 · GenBioPro, Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 43393-0200-60 · GenBioPro, Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 50268-0555-60 · AvPAK · $0.71894 per EA · eff. 2026-09-23 filed
- 59762-5008-01 · Mylan Pharmaceuticals Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 59762-5008-02 · Mylan Pharmaceuticals Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 60687-0746-01 · American Health Packaging · $0.71894 per EA · eff. 2026-09-23 filed
- 60687-0746-11 · not listed as a package in the FDA directory · $0.71894 per EA · eff. 2026-09-23 filed
- 70954-0444-10 · ANI Pharmaceuticals, Inc. · $0.71894 per EA · eff. 2026-09-23 filed
- 70954-0444-20 · ANI Pharmaceuticals, Inc. · $0.71894 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name misoprostol with MISOPROSTOL 200 MCG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| MISOPROSTOL 100 MCG TABLET | $0.4645 per EA filed | $0.67069 per EA filed |
| MISOPROSTOL 200 MCG TABLET this page | $0.71894 per EA filed | $0.67069 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
The middle of its 11 NDCs’ NADAC prices is $0.71894 per EA filed.
Of the 5 other products in FDA’s Prostaglandin E1 Analog class priced per EA, 3 have a higher middle NADAC price and 2 a lower one. The one in the middle is DICLOFENAC-MISOPROSTOL DR 75-0.2 MG TABLET, at $0.96624 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $20.12 for 30 tablets, at an average of $0.67069 per EA in 2024 (2024-01-01 to 2024-12-31) for “Misoprostol”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 91,192 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for MISOPROSTOL 200 MCG TABLET labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Misoprostol / Misoprostol: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.