NAPROXEN DR 375 MG TABLET
For 30 tablets
Pharmacies pay
$67.03 filed
30 × $2.23429 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$82.08 estimated
$67.03 + $10.05 (15%) + $5.00 fee per fill = $82.08
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23, 2026-09-30 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
NAPROXEN DR 375 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as naproxen.
FDA gives its dosage form as “tablet” and “tablet, delayed release” and its route as oral.
Its labelers, the companies named on the label, are Cameron Pharmaceuticals, Aurobindo Pharma Limited and ANI Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Nonsteroidal Anti-inflammatory Drug.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $67.03 for 30 tablets (30 × $2.23429 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-09-23 and 2026-09-30. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
What NADAC measures · Why 30 tablets · NADAC explanation codes
All 3 NDCs
- 42494-0453-10 · Cameron Pharmaceuticals · $2.23429 per EA · eff. 2026-09-23 filed
- 59651-0986-01 · Aurobindo Pharma Limited · $2.23429 per EA · eff. 2026-09-30 filed
- 70954-0925-10 · ANI Pharmaceuticals, Inc. · $2.23429 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
5 other products in the NADAC file share the FDA nonproprietary name naproxen with NAPROXEN DR 375 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| NAPROXEN 125 MG/5 ML SUSPEN | $0.12157 to $0.20183 per ML filed | We don’t know yet |
| NAPROXEN 250 MG TABLET | $0.04356 per EA filed | We don’t know yet |
| NAPROXEN 375 MG TABLET | $0.05884 per EA filed | We don’t know yet |
| NAPROXEN 500 MG TABLET | $0.05654 per EA filed | We don’t know yet |
| NAPROXEN DR 375 MG TABLET this page | $2.23429 per EA filed | We don’t know yet |
| NAPROXEN DR 500 MG TABLET | $1.84147 per EA filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
The middle of its 3 NDCs’ NADAC prices is $2.23429 per EA filed.
Of the 154 other products in FDA’s Nonsteroidal Anti-inflammatory Drug class priced per EA, 23 have a higher middle NADAC price and 131 a lower one. The one in the middle is INDOMETHACIN 25 MG CAPSULE, at $0.09341 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23, 2026-09-30 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic class
Related in the same class
- IBUPROFEN 400 MG TABLET
- CELECOXIB 100 MG CAPSULE
- NABUMETONE 500 MG TABLET
- DICLOFENAC POT 25 MG TABLET
- INDOMETHACIN 25 MG CAPSULE