NICOTINE 21 MG/24HR PATCH
For 1 unit (EA)
Pharmacies pay
$1.87 filed
1 × $1.87251 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$7.15 estimated
$1.87 + $0.28 (15%) + $5.00 fee per fill = $7.15
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
NICOTINE 21 MG/24HR PATCH is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “nicotine”, “nicotine transdermal system” and “nicotine transdermal system patch”, as its NDCs’ listings variously write the nonproprietary name, under the trade names “Nicotine Transdermal System Patch Step 1” and “Nicotine Transdermal System step 1”.
FDA gives its dosage form as “patch, extended release”, “patch” and “film, extended release” and its route as transdermal.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Rugby Laboratories, Dr. Reddy's Laboratories Inc. and AmerisourceBergen Drug Corporation.
FDA’s Established Pharmacologic Class for it is Cholinergic Nicotinic Agonist.
The NADAC file of 2026-10-14 prices it under 25 NDCs (National Drug Codes); the FDA directory lists 24 of them.
NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.87 for 1 unit (EA) (1 × $1.87251 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · NADAC explanation codes
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| BluePoint Laboratories | 6 | $1.87251 per EA filed |
| Rugby Laboratories | 4 | $1.87251 per EA filed |
| Dr. Reddy's Laboratories Inc. | 3 | $1.87251 per EA filed |
| Ingenus Pharmaceuticals, LLC | 3 | $1.87251 per EA filed |
| CARDINAL HEALTH 110, LLC. DBA LEADER | 2 | $1.87251 per EA filed |
| Cardinal Health | 2 | $1.87251 per EA filed |
| Strategic Sourcing Services LLC | 2 | $1.87251 per EA filed |
| AmerisourceBergen Drug Corporation | 1 | $1.87251 per EA filed |
| EXELAN PHARMACEUTICALS, INC. | 1 | $1.87251 per EA filed |
| Not listed as a package in the FDA directory | 1 | $1.87251 per EA filed |
All 25 NDCs, with labeler and price
- 00536-1108-88 · Rugby Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 00536-5896-53 · Rugby Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 00536-5896-71 · Rugby Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 00536-5896-88 · Rugby Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 43598-0448-28 · Dr. Reddy's Laboratories Inc. · $1.87251 per EA · eff. 2026-09-23 filed
- 43598-0448-70 · Dr. Reddy's Laboratories Inc. · $1.87251 per EA · eff. 2026-09-23 filed
- 43598-0448-71 · not listed as a package in the FDA directory · $1.87251 per EA · eff. 2026-09-23 filed
- 43598-0448-74 · Dr. Reddy's Laboratories Inc. · $1.87251 per EA · eff. 2026-09-23 filed
- 46122-0353-74 · AmerisourceBergen Drug Corporation · $1.87251 per EA · eff. 2026-09-23 filed
- 50742-0670-07 · Ingenus Pharmaceuticals, LLC · $1.87251 per EA · eff. 2026-09-23 filed
- 50742-0670-14 · Ingenus Pharmaceuticals, LLC · $1.87251 per EA · eff. 2026-09-23 filed
- 50742-0670-28 · Ingenus Pharmaceuticals, LLC · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0434-88 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0434-90 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0434-91 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0699-88 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0699-90 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 68001-0699-91 · BluePoint Laboratories · $1.87251 per EA · eff. 2026-09-23 filed
- 70000-0512-01 · Cardinal Health · $1.87251 per EA · eff. 2026-09-23 filed
- 70000-0512-02 · Cardinal Health · $1.87251 per EA · eff. 2026-09-23 filed
- 70000-0762-01 · CARDINAL HEALTH 110, LLC. DBA LEADER · $1.87251 per EA · eff. 2026-09-23 filed
- 70000-0762-02 · CARDINAL HEALTH 110, LLC. DBA LEADER · $1.87251 per EA · eff. 2026-09-23 filed
- 70677-1266-01 · Strategic Sourcing Services LLC · $1.87251 per EA · eff. 2026-09-23 filed
- 70677-1266-02 · Strategic Sourcing Services LLC · $1.87251 per EA · eff. 2026-09-23 filed
- 76282-0783-40 · EXELAN PHARMACEUTICALS, INC. · $1.87251 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
8 other products in the NADAC file share an FDA nonproprietary name with NICOTINE 21 MG/24HR PATCH.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| FT NICOTINE 7 MG/24HR PATCH | $1.81971 per EA filed | We don’t know yet |
| FT NICOTINE 14 MG/24HR PATCH | $1.85466 per EA filed | We don’t know yet |
| FT NICOTINE 21 MG/24HR PATCH | $1.87251 per EA filed | We don’t know yet |
| GNP NICOTINE 21 MG/24HR PATCH | $1.87251 per EA filed | We don’t know yet |
| NICOTINE 7 MG/24HR PATCH | $1.81971 per EA filed | We don’t know yet |
| NICOTINE 14 MG/24HR PATCH | $1.85466 per EA filed | We don’t know yet |
| NICOTINE 21 MG/24HR PATCH this page | $1.87251 per EA filed | We don’t know yet |
| NICOTINE TRANSDERMAL SYSTEM | $1.37689 per EA filed | We don’t know yet |
| NICOTROL NS 10 MG/ML SPRAY | $12.956 per ML filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Compared with its class
The middle of its 25 NDCs’ NADAC prices is $1.87251 per EA filed.
Of the 30 other products in FDA’s Cholinergic Nicotinic Agonist class priced per EA, 0 have a higher middle NADAC price and 28 a lower one; 2 have the same. The one in the middle is GS NICOTINE 2 MG LOZENGE, at $0.34675 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists 24 of its 25 NDCs (it does not list the other one) as dosage forms “FILM, EXTENDED RELEASE”, “PATCH”, “PATCH, EXTENDED RELEASE” with route “TRANSDERMAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.