OpenBilldrug price receipt

NADAC week of 2026-10-14

NIGHT TIME COLD-FLU LIQUID

FDA nonproprietary name: acetaminophen, dextromethorphan hbr, doxylamine succinate

For 1 mL

Pharmacies pay

$0.01 – $0.02 filed

1 × $0.01058 to $0.01503 per ML (the 3 NDCs differ)

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.


The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$5.01 – $5.02 estimated

NADAC for the pack + 15% + $5.00 fee per fill

This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

NIGHT TIME COLD-FLU LIQUID is how the CMS NADAC file names this product. The FDA NDC Directory lists it as acetaminophen, dextromethorphan hbr, doxylamine succinate, under the trade names “good neighbor pharmacy night time” and “good neighbor pharmacy night time cold and flu”.

FDA gives its dosage form as solution and its route as oral.

The labeler, the company named on the label, is Amerisource Bergen.

FDA lists it under 3 Established Pharmacologic Classes: Antihistamine, Sigma-1 Agonist and Uncompetitive N-methyl-D-aspartate Receptor Antagonist.

The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and marks it as sold over the counter.

What pharmacies pay

Pharmacies pay $0.01 – $0.02 for 1 mL, depending on the NDC ($0.01058 to $0.01503 per ML), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.

All 3 NDCs

Other strengths, forms and brands

5 other products in the NADAC file share the FDA nonproprietary name acetaminophen, dextromethorphan hbr, doxylamine succinate with NIGHT TIME COLD-FLU LIQUID.

ProductPharmacies pay per unitMedicare per unit
ALL-NITE COLD-FLU RELIEF LIQ
generic · solution
$0.01503 per ML filed
eff. 2026-09-23
We don’t know yet
FT NIGHTTIME COLD-FLU RLF LIQ
generic · solution
$0.01058 to $0.01503 per ML filed
eff. 2026-09-23
We don’t know yet
GS NIGHTTIME COLD-FLU LIQUID
generic · solution
$0.01503 per ML filed
eff. 2026-09-23
We don’t know yet
GS NIGHTTIME COLD-FLU SOFTGEL
generic · capsule, liquid filled
$0.11915 per EA filed
eff. 2026-09-23
We don’t know yet
NIGHT TIME COLD-FLU LIQUID this page
generic · solution
$0.01058 to $0.01503 per ML filed
eff. 2026-09-23
We don’t know yet
NIGHT TIME COLD-FLU SOFTGEL
generic · capsule, liquid filled
$0.11915 per EA filed
eff. 2026-09-23
We don’t know yet

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Compared with its class

The middle of its 3 NDCs’ NADAC prices is $0.01503 per ML filed.

Of the 6 other products in FDA’s Antihistamine class priced per ML, 2 have a higher middle NADAC price and 2 a lower one; 2 have the same. The one in the middle is ALL-NITE COLD-FLU RELIEF LIQ, at $0.01503 per ML filed (eff. 2026-09-23).

Of the 63 other products in FDA’s Sigma-1 Agonist class priced per ML, 49 have a higher middle NADAC price and 12 a lower one; 2 have the same. The one in the middle is QC COUGH RELIEF 15 MG/5 ML LIQ, at $0.02263 per ML filed (eff. 2026-09-23).

Of the 63 other products in FDA’s Uncompetitive N-methyl-D-aspartate Receptor Antagonist class priced per ML, 49 have a higher middle NADAC price and 12 a lower one; 2 have the same. The one in the middle is QC COUGH RELIEF 15 MG/5 ML LIQ, at $0.02263 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

We don’t know yet; the card above says why.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why does this page start at 1 mL?
The FDA package descriptions of this product’s NDCs give different amounts (237 mL, 355 mL). So the card starts at 1 ML; change it to match your prescription.