ONDANSETRON HCL 4 MG/2 ML VIAL
For 2 mL
Pharmacies pay
$0.35 filed
2 × $0.17588 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$0.34 derived
2 × $0.168 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.96× estimated
Medicare pays about what pharmacies pay.
13 labelers share HCPCS J2405 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$5.40 estimated
$0.35 + $0.05 (15%) + $5.00 fee per fill = $5.40
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ONDANSETRON HCL 4 MG/2 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “ondansetron” and “ondansetron hydrochloride”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “injection, solution”, “injection” and “solution” and its route as intramuscular; intravenous.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Hospira, Inc., Hikma Pharmaceuticals USA Inc. and Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
FDA’s Established Pharmacologic Class for it is Serotonin-3 Receptor Antagonist.
The NADAC file of 2026-10-14 prices it under 14 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.35 for 2 mL (2 × $0.17588 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Hospira, Inc. | 3 | $0.17588 per ML filed |
| Fresenius Kabi USA, LLC | 2 | $0.17588 per ML filed |
| Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | 2 | $0.17588 per ML filed |
| Hikma Pharmaceuticals USA Inc. | 2 | $0.17588 per ML filed |
| Apotex Corp. | 1 | $0.17588 per ML filed |
| Baxter Healthcare Corporation | 1 | $0.17588 per ML filed |
| Civica, Inc. | 1 | $0.17588 per ML filed |
| Fosun Pharma USA Inc. | 1 | $0.17588 per ML filed |
| Sagent Pharmaceuticals | 1 | $0.17588 per ML filed |
All 14 NDCs, with labeler and price
- 00409-0009-25 · Hospira, Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 00409-2271-25 · Hospira, Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 00409-4755-03 · Hospira, Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 00641-6078-25 · Hikma Pharmaceuticals USA Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 00641-6080-25 · Hikma Pharmaceuticals USA Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 23155-0547-42 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 23155-0548-42 · Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 25021-0777-02 · Sagent Pharmaceuticals · $0.17588 per ML · eff. 2026-09-23 filed
- 36000-0012-25 · Baxter Healthcare Corporation · $0.17588 per ML · eff. 2026-09-23 filed
- 60505-6130-05 · Apotex Corp. · $0.17588 per ML · eff. 2026-09-23 filed
- 63323-0373-02 · Fresenius Kabi USA, LLC · $0.17588 per ML · eff. 2026-09-23 filed
- 65219-0323-02 · Fresenius Kabi USA, LLC · $0.17588 per ML · eff. 2026-09-23 filed
- 72266-0123-25 · Fosun Pharma USA Inc. · $0.17588 per ML · eff. 2026-09-23 filed
- 72572-0520-25 · Civica, Inc. · $0.17588 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
6 other products in the NADAC file share an FDA nonproprietary name with ONDANSETRON HCL 4 MG/2 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ONDANSETRON 4 MG/5 ML SOLUTION | $0.28641 per ML filed | $0.0128 per ML derived |
| ONDANSETRON 40 MG/20 ML VIAL | $0.17297 per ML filed | $0.168 per ML derived |
| ONDANSETRON HCL 4 MG TABLET | $0.05824 per EA filed | $0.064 per EA derived |
| ONDANSETRON HCL 4 MG/2 ML VIAL this page | $0.17588 per ML filed | $0.168 per ML derived |
| ONDANSETRON HCL 8 MG TABLET | $0.07811 per EA filed | $0.128 per EA derived |
| ONDANSETRON ODT 4 MG TABLET | $0.11992 per EA filed | $0.50024 per EA filed |
| ONDANSETRON ODT 8 MG TABLET | $0.16863 per EA filed | $0.50024 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
What Medicare paid
Medicare Part B’s payment limit for HCPCS J2405, for 2026-10-01 to 2026-12-31, comes to $0.34 for 2 mL, or $0.168 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0168 per 1 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 2 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 2 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 2 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, 14 of this product’s NDCs are wholesale packs of identical units, so OpenBill counts one unit of each; for example, NDC 00409-0009-25 (“25 VIAL, SINGLE-DOSE in 1 TRAY (0409-0009-25) / 2 mL in 1 VIAL, SINGLE-DOSE (0409-0009-02)”) is a tray of 25 vials, 50 mL in all. So the card starts at one unit: 2 ML. Change it to match your prescription.