ORPHENADRINE 60 MG/2 ML VIAL
For 1 mL
Pharmacies pay
$5.73 – $7.07 filed
1 × $5.73029 to $7.0744 per ML (the 3 NDCs differ)
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-07-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$6.55 filed
1 × $6.55317 per ML, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
0.93× – 1.1× estimated
Medicare paid between 0.93× and 1.1× what pharmacies pay, depending on the NDC.
Part D averages every strength and form sold under “Orphenadrine Citrate” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-07-22, 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$11.59 – $13.13 estimated
NADAC for the pack + 15% + $5.00 fee per fill
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-07-22, 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
ORPHENADRINE 60 MG/2 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as orphenadrine citrate.
FDA gives its dosage form as “injection” and “injection, solution” and its route as intramuscular; intravenous.
Its labelers, the companies named on the label, are Hikma Pharmaceuticals USA Inc. and Sagent Pharmaceuticals.
FDA’s Established Pharmacologic Class for it is Muscle Relaxant.
The NADAC file of 2026-10-14 prices it under 3 NDCs (National Drug Codes); the FDA directory lists 2 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $5.73 – $7.07 for 1 mL, depending on the NDC ($5.73029 to $7.0744 per ML), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-07-22 and 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 4, carried forward from the previous file; 5, calculated based on package size.
The NADAC of 1 of these 3 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-07-22. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
All 3 NDCs
- 00641-6182-10 · not listed as a package in the FDA directory · $5.73029 per ML · eff. 2026-09-23 filed
- 00641-6182-25 · Hikma Pharmaceuticals USA Inc. · $7.0744 per ML · eff. 2026-07-22 filed carried forward
- 25021-0651-02 · Sagent Pharmaceuticals · $5.73029 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name orphenadrine citrate with ORPHENADRINE 60 MG/2 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| ORPHENADRINE 60 MG/2 ML VIAL this page | $5.73029 to $7.0744 per ML filed | $6.55317 per ML filed |
| ORPHENADRINE ER 100 MG TABLET | $0.45364 per EA filed | $0.76505 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-07-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
What Medicare paid
Medicare Part D paid $6.55 for 1 mL, at an average of $6.55317 per ML in 2024 (2024-01-01 to 2024-12-31) for “Orphenadrine Citrate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 4,522 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- Which NDC (the 11-digit number on the package) is this? Pharmacies pay $5.73029 to $7.0744 per ML for this product, depending on the NDC.
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for ORPHENADRINE 60 MG/2 ML VIAL labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Orphenadrine Citrate / Orphenadrine Citrate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on generic name.
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (20 mL, 500 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- CYCLOBENZAPRINE 10 MG TABLET
- METHOCARBAMOL 1,000 MG TABLET
- CARISOPRODOL 250 MG TABLET
- METAXALONE 400 MG TABLET
- CHLORZOXAZONE 250 MG TABLET