PHENYLEPHRINE 2.5% EYE DROP

What it is

PHENYLEPHRINE 2.5% EYE DROP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as phenylephrine hydrochloride.

FDA gives its dosage form as “solution/ drops” and “solution” and its route as ophthalmic.

FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Alcon Laboratories, Inc., Caplin Steriles Limited and Leading Pharma, LLC.

FDA’s Established Pharmacologic Class for it is alpha-1 Adrenergic Agonist.

The NADAC file of 2026-10-14 prices it under 7 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $18.58 for 2 mL (2 × $9.29238 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

The 7 labelers

Other strengths, forms and brands

4 other products in the NADAC file share the FDA nonproprietary name phenylephrine hydrochloride with PHENYLEPHRINE 2.5% EYE DROP.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 7 NDCs’ NADAC prices is $9.29238 per ML filed.

Of the 30 other products in FDA’s alpha-1 Adrenergic Agonist class priced per ML, 0 have a higher middle NADAC price and 30 a lower one. The one in the middle is RYNEX DM LIQUID, at $0.05121 per ML filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $26.32 for 2 mL, at an average of $13.16058 per ML in 2024 (2024-01-01 to 2024-12-31) for “Phenylephrine HCl*” and “Phenylephrine HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 1,144 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 2 mL? Is it lower than what I would pay through my insurance?
• How much is in the package I am getting? This page uses 2 mL; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.