PIPERACIL-TAZOBACT 3.375 GM VL
FDA nonproprietary name: piperacillin sodium,tazobactam sodium
For 1 unit (EA)
Pharmacies pay
$3.49 filed
1 × $3.49257 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-21 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D paid
$4.05 filed
1 × $4.04535 per EA, Part D average
Medicare's price is not your price.
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
The spread
1.2× estimated
Medicare paid 1.2× what pharmacies pay.
Part D averages every strength and form sold under “Piperacillin-Tazobactam” / “Piperacillin Sodium/Tazobactam” into one figure, so it is not specific to this NDC.
OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-21 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)
Cost-plus estimate
$9.01 estimated
$3.49 + $0.52 (15%) + $5.00 fee per fill = $9.01
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-01-21 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PIPERACIL-TAZOBACT 3.375 GM VL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “piperacillin sodium,tazobactam sodium”, “piperacillin and tazobactam” and “piperacillin sodium and tazobactam sodium”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “injection, powder, lyophilized, for solution” and “injection, powder, for solution” and its route as “intravenous; parenteral” and “intravenous”.
FDA lists 9 labelers (the companies named on the label) for its NDCs, among them Sandoz Inc, WG Critical Care, LLC and Eugia US LLC.
FDA lists it under 2 Established Pharmacologic Classes: beta Lactamase Inhibitor and Penicillin-class Antibacterial.
The NADAC file of 2026-10-14 prices it under 12 NDCs (National Drug Codes); the FDA directory lists 11 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $3.49 for 1 unit (EA) (1 × $3.49257 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-01-21. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.
The NADAC of all 12 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-01-21. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
The 9 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Fresenius Kabi USA, LLC | 3 | $3.49257 per EA filed |
| Apotex Corp. | 1 | $3.49257 per EA filed |
| Armas Pharmaceuticals Inc. | 1 | $3.49257 per EA filed |
| BluePoint Laboratories | 1 | $3.49257 per EA filed |
| Civica, Inc. | 1 | $3.49257 per EA filed |
| Eugia US LLC | 1 | $3.49257 per EA filed |
| Provepharm Inc. | 1 | $3.49257 per EA filed |
| Sandoz Inc | 1 | $3.49257 per EA filed |
| WG Critical Care, LLC | 1 | $3.49257 per EA filed |
| Not listed as a package in the FDA directory | 1 | $3.49257 per EA filed |
All 12 NDCs, with labeler and price
- 00781-3113-95 · Sandoz Inc · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 44567-0802-10 · WG Critical Care, LLC · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 55150-0120-30 · Eugia US LLC · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 60505-6157-04 · Apotex Corp. · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 61990-0120-02 · not listed as a package in the FDA directory · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 63323-0983-21 · Fresenius Kabi USA, LLC · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 63323-0983-53 · Fresenius Kabi USA, LLC · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 65219-0436-20 · Fresenius Kabi USA, LLC · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 68001-0507-82 · BluePoint Laboratories · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 72485-0403-10 · Armas Pharmaceuticals Inc. · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 72572-0573-10 · Civica, Inc. · $3.49257 per EA · eff. 2026-01-21 filed carried forward
- 81284-0152-10 · Provepharm Inc. · $3.49257 per EA · eff. 2026-01-21 filed carried forward
Compared with its class
The middle of its 12 NDCs’ NADAC prices is $3.49257 per EA filed.
Of the 4 other products in FDA’s beta Lactamase Inhibitor class priced per EA, 1 has a higher middle NADAC price and 3 a lower one. The one in the middle is AMOX-CLAV 875-125 MG TABLET, at $0.28385 per EA filed (eff. 2026-09-23).
Of the 16 other products in FDA’s Penicillin-class Antibacterial class priced per EA, 2 have a higher middle NADAC price and 14 a lower one. The one in the middle is AMOX-CLAV 500-125 MG TABLET, at $0.25341 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-21, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part D paid $4.05 for 1 unit (EA), at an average of $4.04535 per EA in 2024 (2024-01-01 to 2024-12-31) for “Piperacillin-Tazobactam” and “Piperacillin Sodium/Tazobactam”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).
That average covers 72,722 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.
11 of the product’s 12 NDCs have this Medicare figure; the other 1 do not, and the interactive card says why for each.
Medicare's price is not your price.
What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
- If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why is the comparison with Medicare for PIPERACIL-TAZOBACT 3.375 GM VL labelled estimated?
- Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Piperacillin-Tazobactam / Piperacillin Sodium/Tazobactam: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
- Why does this page start at 1 unit (EA)?
- NADAC prices this product per EA, and the FDA NDC Directory lists 11 of its 12 NDCs (it does not list the other one) as dosage forms “INJECTION, POWDER, FOR SOLUTION”, “INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION” with routes “INTRAVENOUS”, “INTRAVENOUS; PARENTERAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.
Related pages
Its pharmacologic classes
Related in the same class
- AMOX-CLAV 200-28.5 MG/5 ML SUS
- DICLOXACILLIN 250 MG CAPSULE
- AMOXICILLIN 125 MG TAB CHEW
- AMPICILLIN 500 MG CAPSULE
- PENICILLIN VK 125 MG/5 ML SOLN