OpenBilldrug price receipt

NADAC week of 2026-10-14

PRAMIPEXOLE ER 0.375 MG TABLET

For 30 tablets

Pharmacies pay

$28.45 filed

30 × $0.94832 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$177.41 filed

30 × $5.91355 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

6.2× estimated

Medicare paid 6.2× what pharmacies pay.

Part D averages every strength and form sold under “Pramipexole ER” / “Pramipexole Di-HCl” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$37.72 estimated

$28.45 + $4.27 (15%) + $5.00 fee per fill = $37.72

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

PRAMIPEXOLE ER 0.375 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as pramipexole dihydrochloride, under the trade name “Pramipexole Dihydrochloride Extended-Release”.

FDA gives its dosage form as tablet, extended release and its route as oral.

FDA lists 6 labelers (the companies named on the label) for its NDCs, among them NorthStar RxLLC, Macleods Pharmaceuticals Limited and Ingenus Pharmaceuticals, LLC.

FDA’s Established Pharmacologic Class for it is Nonergot Dopamine Agonist.

The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $28.45 for 30 tablets (30 × $0.94832 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

All 6 NDCs

Other strengths, forms and brands

12 other products in the NADAC file share the FDA nonproprietary name pramipexole dihydrochloride with PRAMIPEXOLE ER 0.375 MG TABLET.

ProductPharmacies pay per unitMedicare per unit
PRAMIPEXOLE 0.125 MG TABLET
generic · tablet
$0.03943 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE 0.25 MG TABLET
generic · tablet
$0.04517 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE 0.5 MG TABLET
generic · tablet
$0.05665 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE 0.75 MG TABLET
generic · tablet
$0.07211 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE 1 MG TABLET
generic · tablet
$0.06192 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE 1.5 MG TABLET
generic · tablet
$0.06049 per EA filed
eff. 2026-09-23
$0.14611 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 0.375 MG TABLET this page
generic · tablet, extended release
$0.94832 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 0.75 MG TABLET
generic · tablet, extended release
$0.71785 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 1.5 MG TABLET
generic · tablet, extended release
$1.68274 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 2.25 MG TABLET
generic · tablet, extended release
$1.46337 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 3 MG TABLET
generic · tablet, extended release
$1.47943 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 3.75 MG TABLET
generic · tablet, extended release
$2.38933 per EA filed
eff. 2025-10-22
$5.91355 per EA filed
Part D 2024 average
PRAMIPEXOLE ER 4.5 MG TABLET
generic · tablet, extended release
$1.65977 per EA filed
eff. 2026-09-23
$5.91355 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 6 NDCs’ NADAC prices is $0.94832 per EA filed.

Of the 30 other products in FDA’s Nonergot Dopamine Agonist class priced per EA, 13 have a higher middle NADAC price and 17 a lower one. The one in the middle is ROPINIROLE HCL ER 4 MG TABLET, at $0.4617 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $177.41 for 30 tablets, at an average of $5.91355 per EA in 2024 (2024-01-01 to 2024-12-31) for “Pramipexole ER” and “Pramipexole Di-HCl”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 28,008 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for PRAMIPEXOLE ER 0.375 MG TABLET labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Pramipexole ER / Pramipexole Di-HCl: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.