OpenBilldrug price receipt

NADAC week of 2026-10-14

PREMARIN 0.625 MG TABLET

FDA nonproprietary name: estrogens, conjugated

For 30 tablets

Pharmacies pay

$208.29 filed

30 × $6.94289 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$323.50 filed

30 × $10.78328 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18


The spread

1.6× estimated

Medicare paid 1.6× what pharmacies pay.

Part D averages every strength and form sold under “Premarin*” / “Estrogens, Conjugated” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$244.53 estimated

$208.29 + $31.24 (15%) + $5.00 fee per fill = $244.53

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

PREMARIN 0.625 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as estrogens, conjugated, under the trade name “Premarin”.

FDA gives its dosage form as tablet, film coated and its route as oral.

The labeler, the company named on the label, is Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.

FDA’s Established Pharmacologic Class for it is Estrogen.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $208.29 for 30 tablets (30 × $6.94289 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $5.46982 per EA filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

All 2 NDCs

Other strengths, forms and brands

9 other products in the NADAC file share the FDA nonproprietary name estrogens, conjugated with PREMARIN 0.625 MG TABLET.

ProductPharmacies pay per unitMedicare per unit
CONJUGATED ESTROGEN 0.625 MG TB
generic · tablet, film coated
$5.46982 per EA filed
eff. 2026-09-23
We don’t know yet
CONJUGATED ESTROGENS 0.3 MG TB
generic · tablet, film coated
$5.37279 per EA filed
eff. 2026-09-23
We don’t know yet
CONJUGATED ESTROGENS 0.45 MG TB
generic · tablet, film coated
$5.4808 per EA filed
eff. 2026-09-23
We don’t know yet
CONJUGATED ESTROGENS 0.9 MG TB
generic · tablet, film coated
$5.57252 per EA filed
eff. 2026-09-23
We don’t know yet
CONJUGATED ESTROGENS 1.25 MG TB
generic · tablet, film coated
$5.47658 per EA filed
eff. 2026-09-23
We don’t know yet
PREMARIN 0.3 MG TABLET
brand · tablet, film coated
$6.94743 per EA filed
eff. 2026-09-23
$10.78328 per EA filed
Part D 2024 average
PREMARIN 0.45 MG TABLET
brand · tablet, film coated
$6.95576 per EA filed
eff. 2026-09-23
$10.78328 per EA filed
Part D 2024 average
PREMARIN 0.625 MG TABLET this page
brand · tablet, film coated
$6.94289 per EA filed
eff. 2026-09-23
$10.78328 per EA filed
Part D 2024 average
PREMARIN 0.9 MG TABLET
brand · tablet, film coated
$6.93133 per EA filed
eff. 2026-09-23
$10.78328 per EA filed
Part D 2024 average
PREMARIN 1.25 MG TABLET
brand · tablet, film coated
$6.95373 per EA filed
eff. 2026-09-23
$10.78328 per EA filed
Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $6.94289 per EA filed.

Of the 104 other products in FDA’s Estrogen class priced per EA, 62 have a higher middle NADAC price and 42 a lower one. The one in the middle is DOTTI 0.0375 MG PATCH, at $8.26227 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What Medicare paid

Medicare Part D paid $323.50 for 30 tablets, at an average of $10.78328 per EA in 2024 (2024-01-01 to 2024-12-31) for “Premarin*” and “Estrogens, Conjugated”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 610,592 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

Questions

Why is the comparison with Medicare for PREMARIN 0.625 MG TABLET labelled estimated?
Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Premarin* / Estrogens, Conjugated: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on brand name. *: CMS says this average reflects multiple routes of administration, which may have different unit prices. All 8 NADAC NDCs the name join matched to it have an FDA route including ORAL.