PROPOFOL 500 MG/50 ML VIAL
For 50 mL
Pharmacies pay
$8.55 filed
50 × $0.17094 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$4.65 derived
50 × $0.093 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.54× estimated
Medicare pays 46% less than pharmacies pay.
13 labelers share HCPCS J2704 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$14.83 estimated
$8.55 + $1.28 (15%) + $5.00 fee per fill = $14.83
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-08-19 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
PROPOFOL 500 MG/50 ML VIAL is how the CMS NADAC file names this product. The FDA NDC Directory lists it as propofol.
FDA gives its dosage form as injection, emulsion and its route as intravenous.
The labeler, the company named on the label, is Meitheal Pharmaceuticals Inc.
FDA’s Established Pharmacologic Class for it is General Anesthetic.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 71288-0730-51.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $8.55 for 50 mL (50 × $0.17094 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-08-19. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size.
This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-08-19. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
The NDC
- 71288-0730-51 · Meitheal Pharmaceuticals Inc. · $0.17094 per ML · eff. 2026-08-19 filed carried forward
Other strengths, forms and brands
1 other product in the NADAC file shares the FDA nonproprietary name propofol with PROPOFOL 500 MG/50 ML VIAL.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| PROPOFOL 200 MG/20 ML VIAL | $0.17094 per ML filed | $0.093 per ML derived |
| PROPOFOL 500 MG/50 ML VIAL this page | $0.17094 per ML filed | $0.093 per ML derived |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-02 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
Its NADAC price is $0.17094 per ML filed.
Of the 4 other products in FDA’s General Anesthetic class priced per ML, 3 have a higher middle NADAC price and 0 a lower one; 1 has the same. The one in the middle is KETAMINE 500 MG/10 ML VIAL, at $0.5563 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J2704, for 2026-10-01 to 2026-12-31, comes to $4.65 for 50 mL, or $0.093 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for a drug like this only in specific settings, such as a drug given in a clinic or doctor’s office or used with certain medical equipment; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0186 per 10 MG.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 50 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 50 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 50 mL?
- NADAC prices this product per ML. In the FDA NDC Directory, NDC 71288-0730-51 (“10 VIAL in 1 CARTON (71288-730-51) / 50 mL in 1 VIAL (71288-730-50)”) is a carton of 10 vials, 500 mL in all: a wholesale pack of identical units, so OpenBill counts one vial of it. So the card starts at one vial: 50 ML. Change it to match your prescription.