REFRESH OPTIVE ADVANCED DROPS
FDA nonproprietary name: carboxymethylcellulose sodium, glycerin, and polysorbate 80
Per unit: no single pack total
Pharmacies pay
$0.44482 per EA; $1.03229 per ML filed
These NDCs are priced per different units (EA, ML), so there is no single pack total for a quantity of 1; see the price for each NDC.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
We don’t know yet
These NDCs are priced per different units (EA, ML), so there is no single pack total for a quantity of 1; see the price for each NDC.
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
REFRESH OPTIVE ADVANCED DROPS is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “carboxymethylcellulose sodium, glycerin, and polysorbate 80” and “carboxymethylcellulose sodium, glycerin, polysorbate 80”, as its NDCs’ listings variously write the nonproprietary name, under the trade name “REFRESH OPTIVE Advanced”.
FDA gives its dosage form as solution/ drops and its route as ophthalmic.
The labeler, the company named on the label, is Allergan, Inc.
FDA’s Established Pharmacologic Class for it is Non-Standardized Chemical Allergen.
The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes).
NADAC classes it as a brand-name drug (rate-setting class B), and marks it as sold over the counter.
What pharmacies pay
Pharmacies pay $0.44482 per EA; $1.03229 per ML for it, depending on the NDC, by the CMS NADAC file of 2026-10-14; that price took effect on 2026-08-19. That is what pharmacies pay their suppliers, not what they charge you.
There is no single total for a pack: These NDCs are priced per different units (EA, ML), so there is no single pack total for a quantity of 1; see the price for each NDC.
NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
The NADAC of all 2 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-08-19. The file is new; the price is not.
What NADAC measures · NADAC explanation codes · Carried-forward prices
All 2 NDCs
- 00023-4307-10 · Allergan, Inc. · $1.03229 per ML · eff. 2026-08-19 filed carried forward
- 00023-4491-30 · Allergan, Inc. · $0.44482 per EA · eff. 2026-08-19 filed carried forward
Other strengths, forms and brands
1 other product in the NADAC file shares an FDA nonproprietary name with REFRESH OPTIVE ADVANCED DROPS.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| REFRESH DIGITAL EYE DROPS | $1.03229 per ML filed | We don’t know yet |
| REFRESH OPTIVE ADVANCED DROPS this page | $0.44482 per EA; $1.03229 per ML filed | We don’t know yet |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-08-19 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for the amount I was prescribed? Is it lower than what I would pay through my insurance?
- It is sold over the counter, so shelf prices vary from store to store: what does it cost per unit here?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic class
Related in the same class
- ARTIFICIAL TEARS 0.1-0.2-0.3%
- CHILD GLYCERIN 1.2 GM SUPP
- DRY EYE RELIEF EYE DROPS
- GENTEAL TEARS 0.1%-0.2%-0.3%
- GNP HEMORRHOIDAL PAIN RLF CRM