Why is the comparison with Medicare for RYCLORA 2 MG/5 ML SOLUTION labelled estimated?

Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Ryclora / Dexchlorpheniramine Maleate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.

Why does this page start at 118 mL?

NADAC prices this product per ML. The FDA NDC Directory’s package description gives 118 mL in one package for this product’s NDC (“118 mL in 1 BOTTLE, PLASTIC (15370-150-04)”), so the card starts at one package: 118 ML. Change it to match your prescription.

RYCLORA 2 MG/5 ML SOLUTION

FDA nonproprietary name: dexchlorpheniramine maleate

For 118 mL

Pharmacies pay

$342.45 filed

118 × $2.90212 per ML

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-02-18 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$304.87 filed

118 × $2.58364 per ML, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

The spread

0.89× estimated

Medicare paid 11% less than pharmacies pay.

Part D averages every strength and form sold under “Ryclora” / “Dexchlorpheniramine Maleate” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-02-18 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$398.82 estimated

$342.45 + $51.37 (15%) + $5.00 fee per fill = $398.82

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-02-18 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

RYCLORA 2 MG/5 ML SOLUTION is how the CMS NADAC file names this product. The FDA NDC Directory lists it as dexchlorpheniramine maleate, under the trade name “RYCLORA”.

FDA gives its dosage form as liquid and its route as oral.

The labeler, the company named on the label, is CARWIN PHARMACEUTICAL ASSOCIATES, LLC.

FDA lists no Established Pharmacologic Class for it.

The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 15370-0150-04.

NADAC classes it in its brand rate-setting class B-ANDA, and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $342.45 for 118 mL (118 × $2.90212 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-02-18. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 4, carried forward from the previous file; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

This NDC’s NADAC was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: it took effect on 2026-02-18. The file is new; the price is not.

What NADAC measures · NADAC explanation codes · Carried-forward prices

The NDC

15370-0150-04 · CARWIN PHARMACEUTICAL ASSOCIATES, LLC · $2.90212 per ML · eff. 2026-02-18 filed carried forward

What Medicare paid

Medicare Part D paid $304.87 for 118 mL, at an average of $2.58364 per ML in 2024 (2024-01-01 to 2024-12-31) for “Ryclora” and “Dexchlorpheniramine Maleate”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 84 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 118 mL? Is it lower than what I would pay through my insurance?
How much is in the package I am getting? This page uses 118 mL; your package may hold a different amount.
If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why is the comparison with Medicare for RYCLORA 2 MG/5 ML SOLUTION labelled estimated?: Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Ryclora / Dexchlorpheniramine Maleate: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's ML. Joined on brand name.
Why does this page start at 118 mL?: NADAC prices this product per ML. The FDA NDC Directory’s package description gives 118 mL in one package for this product’s NDC (“118 mL in 1 BOTTLE, PLASTIC (15370-150-04)”), so the card starts at one package: 118 ML. Change it to match your prescription.