RYTARY ER 48.75 MG-195 MG CAP
FDA nonproprietary name: carbidopa and levodopa
For 30 capsules
Pharmacies pay
$119.51 filed
30 × $3.98378 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare
We don’t know yet
No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.
The spread
We don’t know yet
There is no Medicare figure to compare with, so there is no spread.
Cost-plus estimate
$142.44 estimated
$119.51 + $17.93 (15%) + $5.00 fee per fill = $142.44
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
RYTARY ER 48.75 MG-195 MG CAP is how the CMS NADAC file names this product. The FDA NDC Directory lists it as carbidopa and levodopa, under the trade name “RYTARY”.
FDA gives its dosage form as capsule, extended release and its route as oral.
The labeler, the company named on the label, is Amneal Pharmaceuticals LLC.
FDA’s Established Pharmacologic Class for it is Aromatic Amino Acid.
The NADAC file of 2026-10-14 prices it under one NDC (National Drug Code), 64896-0663-01.
NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $119.51 for 30 capsules (30 × $3.98378 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.
NADAC also lists, on the row of one brand NDC, what pharmacies pay for the generic equivalent, a different product: $3.18794 per EA filed.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What NADAC measures · Why 30 capsules · NADAC explanation codes
The NDC
- 64896-0663-01 · Amneal Pharmaceuticals LLC · $3.98378 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
18 other products in the NADAC file share the FDA nonproprietary name carbidopa and levodopa with RYTARY ER 48.75 MG-195 MG CAP.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| CARBIDOPA-LEVO 25-100 MG ODT | $0.68655 per EA filed | We don’t know yet |
| CARBIDOPA-LEVO ER 23.75-95 CAP | $3.15323 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVO ER 25-100 TAB | $0.11014 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVO ER 36.25-145 CP | $3.3941 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVO ER 48.75-195 CP | $3.18794 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVO ER 50-200 TAB | $0.17959 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVO ER 61.25-245 CP | $3.92786 per EA filed | $0.35658 per EA filed |
| CARBIDOPA-LEVODOPA 10-100 TAB | $0.06826 per EA filed | $0.138 per EA filed |
| CARBIDOPA-LEVODOPA 25-100 TAB | $0.07589 per EA filed | $0.138 per EA filed |
| CARBIDOPA-LEVODOPA 25-250 TAB | $0.11894 per EA filed | $0.138 per EA filed |
| CREXONT ER 35 MG-140 MG CAP | $4.58989 per EA filed | We don’t know yet |
| CREXONT ER 52.5 MG-210 MG CAP | $4.5824 per EA filed | We don’t know yet |
| CREXONT ER 70 MG-280 MG CAP | $4.58002 per EA filed | We don’t know yet |
| CREXONT ER 87.5 MG-350 MG CAP | $4.58252 per EA filed | We don’t know yet |
| RYTARY ER 23.75 MG-95 MG CAP | $3.98069 per EA filed | We don’t know yet |
| RYTARY ER 36.25 MG-145 MG CAP | $3.9763 per EA filed | We don’t know yet |
| RYTARY ER 48.75 MG-195 MG CAP this page | $3.98378 per EA filed | We don’t know yet |
| RYTARY ER 61.25 MG-245 MG CAP | $4.99716 per EA filed | We don’t know yet |
| SINEMET 25-100 MG TABLET | $1.42358 per EA filed | $1.28606 per EA filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-07-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
Compared with its class
Its NADAC price is $3.98378 per EA filed.
Of the 25 other products in FDA’s Aromatic Amino Acid class priced per EA, 5 have a higher middle NADAC price and 20 a lower one. The one in the middle is SINEMET 25-100 MG TABLET, at $1.42358 per EA filed (eff. 2026-01-01).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-01-01, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
We don’t know yet; the card above says why.
Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.