SILVADENE 1% CREAM

What it is

SILVADENE 1% CREAM is how the CMS NADAC file names this product. The FDA NDC Directory lists it as silver sulfadiazine, under the trade name “SILVADENE”.

FDA gives its dosage form as cream and its route as topical.

The labeler, the company named on the label, is Pfizer Laboratories Div Pfizer Inc.

FDA’s Established Pharmacologic Class for it is Sulfonamide Antibacterial.

The NADAC file of 2026-10-14 prices it under 6 NDCs (National Drug Codes).

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $0.12 – $0.43 for 1 g, depending on the NDC ($0.12469 to $0.43283 per GM), by the CMS NADAC file of 2026-10-14; those prices took effect between 2026-07-01 and 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 4, carried forward from the previous file; 5, calculated based on package size.

The NADAC of 4 of these 6 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2026-07-01, 2026-08-19. The file is new; the price is not.

NADAC also lists, on the row of its brand NDCs, what pharmacies pay for the generic equivalent, a different product: $0.12781 to $0.40717 per GM filed.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

What NADAC measures · NADAC explanation codes · Carried-forward prices

All 6 NDCs

• 61570-0131-20 · Pfizer Laboratories Div Pfizer Inc · $0.43283 per GM · eff. 2026-08-19 filed carried forward
• 61570-0131-25 · Pfizer Laboratories Div Pfizer Inc · $0.28856 per GM · eff. 2026-07-01 filed carried forward
• 61570-0131-40 · Pfizer Laboratories Div Pfizer Inc · $0.12469 per GM · eff. 2026-07-01 filed carried forward
• 61570-0131-50 · Pfizer Laboratories Div Pfizer Inc · $0.23076 per GM · eff. 2026-09-23 filed
• 61570-0131-55 · Pfizer Laboratories Div Pfizer Inc · $0.23076 per GM · eff. 2026-09-23 filed
• 61570-0131-85 · Pfizer Laboratories Div Pfizer Inc · $0.27318 per GM · eff. 2026-07-01 filed carried forward

Other strengths, forms and brands

2 other products in the NADAC file share the FDA nonproprietary name silver sulfadiazine with SILVADENE 1% CREAM.

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-07-01, 2026-08-19, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 6 NDCs’ NADAC prices is $0.23076 per GM filed.

Of the 7 other products in FDA’s Sulfonamide Antibacterial class priced per GM, 4 have a higher middle NADAC price and 3 a lower one. The one in the middle is SILVER SULFADIAZINE 1% CREAM, at $0.25963 per GM filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $0.15 for 1 g, at an average of $0.15281 per GM in 2024 (2024-01-01 to 2024-12-31) for “Silvadene” and “Silver Sulfadiazine”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 1,023 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

• What is your cash price for 1 g? Is it lower than what I would pay through my insurance?
• Which NDC (the 11-digit number on the package) is this? Pharmacies pay $0.12469 to $0.43283 per GM for this product, depending on the NDC.
• Is a generic version available, and would it suit me? NADAC lists a generic with the same ingredient, strength and dosage form by FDA: SILVER SULFADIAZINE 1% CREAM. Ask your pharmacist or prescriber; do not switch on your own.
• How much is in the package I am getting? This page uses 1 g; your package may hold a different amount.
• If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
• These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.