SIROLIMUS 0.5 MG TABLET
For 30 tablets
Pharmacies pay
$25.24 filed
30 × $0.84147 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$9.14 derived
30 × $0.3045 per EA, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.36× estimated
Medicare pays 64% less than pharmacies pay.
11 labelers share HCPCS J7520 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$34.03 estimated
$25.24 + $3.79 (15%) + $5.00 fee per fill = $34.03
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
SIROLIMUS 0.5 MG TABLET is how the CMS NADAC file names this product. The FDA NDC Directory lists it as sirolimus.
FDA gives its dosage form as “tablet, film coated” and “tablet, sugar coated” and its route as oral.
FDA lists 6 labelers (the companies named on the label) for its NDCs, among them NORTHSTAR RX LLC, Mylan Pharmaceuticals Inc. and American Health Packaging.
FDA lists it under 2 Established Pharmacologic Classes: Kinase Inhibitor and mTOR Inhibitor Immunosuppressant.
The NADAC file of 2026-10-14 prices it under 7 NDCs (National Drug Codes); the FDA directory lists 6 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $25.24 for 30 tablets (30 × $0.84147 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.
What NADAC measures · Why 30 tablets · NADAC explanation codes
The 6 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| American Health Packaging | 1 | $0.84147 per EA filed |
| Ascend Laboratories, LLC | 1 | $0.84147 per EA filed |
| Glenmark Pharmaceuticals Inc., USA | 1 | $0.84147 per EA filed |
| Mylan Pharmaceuticals Inc. | 1 | $0.84147 per EA filed |
| NORTHSTAR RX LLC | 1 | $0.84147 per EA filed |
| Zydus Pharmaceuticals USA Inc. | 1 | $0.84147 per EA filed |
| Not listed as a package in the FDA directory | 1 | $0.84147 per EA filed |
All 7 NDCs, with labeler and price
- 16714-0187-01 · NORTHSTAR RX LLC · $0.84147 per EA · eff. 2026-09-23 filed
- 59762-1001-01 · Mylan Pharmaceuticals Inc. · $0.84147 per EA · eff. 2026-09-23 filed
- 60687-0902-11 · not listed as a package in the FDA directory · $0.84147 per EA · eff. 2026-09-23 filed
- 60687-0902-21 · American Health Packaging · $0.84147 per EA · eff. 2026-09-23 filed
- 67877-0746-01 · Ascend Laboratories, LLC · $0.84147 per EA · eff. 2026-09-23 filed
- 68382-0520-01 · Zydus Pharmaceuticals USA Inc. · $0.84147 per EA · eff. 2026-09-23 filed
- 68462-0682-01 · Glenmark Pharmaceuticals Inc., USA · $0.84147 per EA · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share the FDA nonproprietary name sirolimus with SIROLIMUS 0.5 MG TABLET.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| SIROLIMUS 0.5 MG TABLET this page | $0.84147 per EA filed | $0.3045 per EA derived |
| SIROLIMUS 1 MG TABLET | $0.72296 per EA filed | $0.609 per EA derived |
| SIROLIMUS 1 MG/ML SOLUTION | $4.39032 per ML filed | $0.609 per ML derived |
| SIROLIMUS 2 MG TABLET | $2.5288 per EA filed | $1.218 per EA derived |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 7 NDCs’ NADAC prices is $0.84147 per EA filed.
Of the 20 other products in FDA’s Kinase Inhibitor class priced per EA, 18 have a higher middle NADAC price and 2 a lower one. The one in the middle is EVEROLIMUS 5 MG TABLET, at $14.77078 per EA filed (eff. 2026-04-22).
Of the 12 other products in FDA’s mTOR Inhibitor Immunosuppressant class priced per EA, 11 have a higher middle NADAC price and 1 a lower one. The one in the middle is EVEROLIMUS 1 MG TABLET, at $5.25295 per EA filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-04-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J7520, for 2026-10-01 to 2026-12-31, comes to $9.14 for 30 tablets, or $0.3045 per EA once converted to NADAC’s unit for this product.
Medicare Part B pays for this oral drug at a pharmacy only in specific circumstances CMS sets for this code; most prescriptions are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.1218 per 1 MG.
4 of the product’s 7 NDCs have this Medicare figure; the other 3 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 tablets? Is it lower than what I would pay through my insurance?
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Related pages
Its pharmacologic classes
Related in the same class
- EVEROLIMUS 0.25 MG TABLET
- IMATINIB MESYLATE 100 MG TAB
- KISQALI 400 MG DAILY DOSE
- OPZELURA 1.5% CREAM
- DASATINIB 100 MG TABLET