Why is the comparison with Medicare for SUMATRIPTAN 20 MG NASAL SPRAY labelled estimated?

Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Sumatriptan / Sumatriptan: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.

Why does this page start at 1 unit (EA)?

NADAC prices this product per EA, and the FDA NDC Directory lists its 4 NDCs as dosage form “SPRAY” with route “NASAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.

SUMATRIPTAN 20 MG NASAL SPRAY

For 1 unit (EA)

Pharmacies pay

$16.51 filed

1 × $16.5061 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D paid

$21.97 filed

1 × $21.97218 per EA, Part D average

Medicare's price is not your price.

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

The spread

1.3× estimated

Medicare paid 1.3× what pharmacies pay.

Part D averages every strength and form sold under “Sumatriptan” into one figure, so it is not specific to this NDC.

OpenBill calculation · DSD_PTD_RY26_P04_V10_DY24_BGM.csv + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part D 2024-01-01 to 2024-12-31 (file of 2026-06-25, retrieved 2026-10-18)

Cost-plus estimate

$23.99 estimated

$16.51 + $2.48 (15%) + $5.00 fee per fill = $23.99

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

SUMATRIPTAN 20 MG NASAL SPRAY is how the CMS NADAC file names this product. The FDA NDC Directory lists it as sumatriptan.

FDA gives its dosage form as spray and its route as nasal.

FDA lists 4 labelers (the companies named on the label) for its NDCs, among them Lannett Company, Inc., Padagis Israel Pharmaceuticals Ltd and Prasco Laboratories.

FDA’s Established Pharmacologic Class for it is Serotonin-1b and Serotonin-1d Receptor Agonist.

The NADAC file of 2026-10-14 prices it under 4 NDCs (National Drug Codes).

NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $16.51 for 1 unit (EA) (1 × $16.5061 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size; 6, the CMS Covered Outpatient Drug Product File S/I/N drug category was not applied when grouping drugs for the calculation.

What NADAC measures · NADAC explanation codes

All 4 NDCs

00527-1859-43 · Lannett Company, Inc. · $16.5061 per EA · eff. 2026-09-23 filed
45802-0598-06 · Padagis Israel Pharmaceuticals Ltd · $16.5061 per EA · eff. 2026-09-23 filed
66993-0082-69 · Prasco Laboratories · $16.5061 per EA · eff. 2026-09-23 filed
69097-0644-48 · Cipla USA Inc. · $16.5061 per EA · eff. 2026-09-23 filed

Other strengths, forms and brands

11 other products in the NADAC file share the FDA nonproprietary name sumatriptan with SUMATRIPTAN 20 MG NASAL SPRAY.

Product	Pharmacies pay per unit	Medicare per unit
IMITREX 4 MG/0.5 ML PEN INJECT brand · injection	$463.07333 per ML filed eff. 2026-09-23	We don’t know yet
IMITREX 6 MG/0.5 ML CARTRIDGES brand · injection	$436.79714 per ML filed eff. 2026-09-23	We don’t know yet
IMITREX 6 MG/0.5 ML PEN INJECT brand · injection	$460.05429 per ML filed eff. 2026-09-23	We don’t know yet
IMITREX 100 MG TABLET brand · tablet, film coated	$72.39673 per EA filed eff. 2026-09-23	We don’t know yet
SUMATRIPTAN 5 MG NASAL SPRAY generic · spray	$17.03859 per EA filed eff. 2026-09-23	$21.97218 per EA filed Part D 2024 average
SUMATRIPTAN 6 MG/0.5 ML AUTOINJ generic · injection / injection, solution	$61.41234 per ML filed eff. 2026-09-23	We don’t know yet
SUMATRIPTAN 6 MG/0.5 ML VIAL generic · injection / injection, solution	$14.93447 to $15.00 per ML filed eff. 2026-07-22 to 2026-09-23	We don’t know yet
SUMATRIPTAN 20 MG NASAL SPRAY this page generic · spray	$16.5061 per EA filed eff. 2026-09-23	$21.97218 per EA filed Part D 2024 average
SUMATRIPTAN SUCC 25 MG TABLET generic · tablet, film coated / tablet	$0.23942 per EA filed eff. 2026-09-23	We don’t know yet
SUMATRIPTAN SUCC 50 MG TABLET generic · tablet, film coated / tablet	$0.30222 per EA filed eff. 2026-09-23 to 2026-09-30	We don’t know yet
SUMATRIPTAN SUCC 100 MG TABLET generic · tablet, film coated / tablet	$0.43878 per EA filed eff. 2026-09-23	We don’t know yet
TOSYMRA 10 MG NASAL SPRAY brand · spray	$108.22118 per EA filed eff. 2026-09-23	$107.19459 per EA filed Part D 2024 average

Part D is one average per brand and generic name, over every strength and form.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. between 2026-07-22 and 2026-09-30 (4 dates) · as of 2026-10-14 · retrieved 2026-10-17

Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18

Compared with its class

The middle of its 4 NDCs’ NADAC prices is $16.5061 per EA filed.

Of the 28 other products in FDA’s Serotonin-1b and Serotonin-1d Receptor Agonist class priced per EA, 11 have a higher middle NADAC price and 17 a lower one. The one in the middle is ZOLMITRIPTAN 2.5 MG ODT, at $2.06825 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

Medicare Part D paid $21.97 for 1 unit (EA), at an average of $21.97218 per EA in 2024 (2024-01-01 to 2024-12-31) for “Sumatriptan”, every strength and form sold under that name together (Medicare Part D Spending by Drug, file of 2026-06-25).

That average covers 48,243 Part D claims (fills, including refills) for 2024-01-01 to 2024-12-31, across every maker, strength and form under the name.

Medicare's price is not your price.

What Part D spending measures · Which Medicare figure OpenBill compares · How the spread is worked out

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 1 unit (EA)? Is it lower than what I would pay through my insurance?
If you have Medicare Part D: what is my plan’s copay or coinsurance for it? The Part D average on this page is not what you pay.
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why is the comparison with Medicare for SUMATRIPTAN 20 MG NASAL SPRAY labelled estimated?: Beyond what the card shows, the records give these reasons: The Part D figure covers 2024-01-01 to 2024-12-31; the NADAC price is from the file of 2026-10-14. Part D spending basis, as the Part D record states it: Part D 2024 average spend per dosage unit for Sumatriptan / Sumatriptan: all makers, strengths, forms and routes combined, claim-weighted; gross cost incl. dispensing fees and patient pay, before rebates. Unit taken as NADAC's EA. Joined on generic name.
Why does this page start at 1 unit (EA)?: NADAC prices this product per EA, and the FDA NDC Directory lists its 4 NDCs as dosage form “SPRAY” with route “NASAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and none of these is one. NADAC’s EA for it may be a whole package (such as a kit, pen, syringe, vial or inhaler) or one dose inside it, and the files do not say which. So the card starts at 1 unit (EA) rather than guess how many make up a fill; change it to match your prescription.

Its pharmacologic class

Serotonin-1b and Serotonin-1d Receptor Agonist 35 products