TEMOZOLOMIDE 250 MG CAPSULE
For 30 capsules
Pharmacies pay
$616.00 filed
30 × $20.5332 per EA
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$312.00 derived
30 × $10.40 per EA, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
0.51× estimated
Medicare pays 49% less than pharmacies pay.
4 labelers share HCPCS J8700 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-10-22 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$713.40 estimated
$616.00 + $92.40 (15%) + $5.00 fee per fill = $713.40
This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2025-10-22 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TEMOZOLOMIDE 250 MG CAPSULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as temozolomide.
FDA gives its dosage form as capsule and its route as oral.
FDA lists 7 labelers (the companies named on the label) for its NDCs, among them Rising Pharma Holdings, Inc., Accord Healthcare Inc. and Camber Pharmaceuticals, Inc.
FDA’s Established Pharmacologic Class for it is Alkylating Drug.
The NADAC file of 2026-10-14 prices it under 8 NDCs (National Drug Codes); the FDA directory lists 7 of them.
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $616.00 for 30 capsules (30 × $20.5332 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2025-10-22. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation code for it: 4, carried forward from the previous file.
The NADAC of all 8 NDCs was carried forward from an earlier file (NADAC explanation code 2 or 4), not newly surveyed: those prices took effect on 2025-10-22. The file is new; the price is not.
What NADAC measures · Why 30 capsules · NADAC explanation codes · Carried-forward prices
The 7 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Accord Healthcare Inc. | 1 | $20.5332 per EA filed |
| Amneal Pharmaceuticals LLC | 1 | $20.5332 per EA filed |
| Ascend Laboratories, LLC | 1 | $20.5332 per EA filed |
| Camber Pharmaceuticals, Inc. | 1 | $20.5332 per EA filed |
| Devatis, Inc. | 1 | $20.5332 per EA filed |
| Rising Pharma Holdings, Inc. | 1 | $20.5332 per EA filed |
| Sun Pharmaceutical Industries, Inc. | 1 | $20.5332 per EA filed |
| Not listed as a package in the FDA directory | 1 | $20.5332 per EA filed |
All 8 NDCs, with labeler and price
- 16571-0821-51 · Rising Pharma Holdings, Inc. · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 16729-0051-53 · Accord Healthcare Inc. · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 31722-0416-31 · Camber Pharmaceuticals, Inc. · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 47335-0893-60 · not listed as a package in the FDA directory · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 47335-0893-74 · Sun Pharmaceutical Industries, Inc. · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 65162-0806-51 · Amneal Pharmaceuticals LLC · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 67877-0542-07 · Ascend Laboratories, LLC · $20.5332 per EA · eff. 2025-10-22 filed carried forward
- 73043-0016-05 · Devatis, Inc. · $20.5332 per EA · eff. 2025-10-22 filed carried forward
Other strengths, forms and brands
2 other products in the NADAC file share the FDA nonproprietary name temozolomide with TEMOZOLOMIDE 250 MG CAPSULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| TEMOZOLOMIDE 20 MG CAPSULE | $0.87977 per EA filed | $0.832 per EA derived |
| TEMOZOLOMIDE 100 MG CAPSULE | $4.37549 per EA filed | $4.16 per EA derived |
| TEMOZOLOMIDE 250 MG CAPSULE this page | $20.5332 per EA filed | $10.40 per EA derived |
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2025-10-22, 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
What Medicare paid
Medicare Part B’s payment limit for HCPCS J8700, for 2026-10-01 to 2026-12-31, comes to $312.00 for 30 capsules, or $10.40 per EA once converted to NADAC’s unit for this product.
Medicare Part B pays for this oral drug at a pharmacy only in specific circumstances CMS sets for this code; most prescriptions are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $0.0416 per 5 MG.
3 of the product’s 8 NDCs have this Medicare figure; the other 5 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 30 capsules? Is it lower than what I would pay through my insurance?
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.