TOBRAMYCIN 300 MG/5 ML AMPULE
For 1 mL
Pharmacies pay
$1.08 filed
1 × $1.084 per ML
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part B pays
$2.28 derived
1 × $2.2808 per ML, Part B limit
Medicare's price is not your price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
The spread
2.1× estimated
Medicare pays 2.1× what pharmacies pay.
15 labelers share HCPCS J7682 on the CMS crosswalk, so its payment limit is an average across all their products billed under that code, not this NDC’s own price.
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip + nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17) · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Cost-plus estimate
$6.24 estimated
$1.08 + $0.16 (15%) + $5.00 fee per fill = $6.24
This is a model, not a price any pharmacy quoted. Shipping is not included. For a pack this cheap, the $5.00 fee is most of the estimate. How it is worked out
OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)
Open the interactive card Change the quantity, type what you were charged, and see every record in full.
What it is
TOBRAMYCIN 300 MG/5 ML AMPULE is how the CMS NADAC file names this product. The FDA NDC Directory lists it as “tobramycin”, “tobramycin inhalation solution” and “tobramycin solution”, as its NDCs’ listings variously write the nonproprietary name.
FDA gives its dosage form as “solution” and “inhalant” and its route as respiratory (inhalation).
FDA lists 10 labelers (the companies named on the label) for its NDCs, among them Teva Pharmaceuticals USA, Inc., Micro Labs Limited and Dr. Reddy's Laboratories Inc.
FDA’s Established Pharmacologic Class for it is Aminoglycoside Antibacterial.
The NADAC file of 2026-10-14 prices it under 11 NDCs (National Drug Codes).
NADAC classes it as a generic drug (rate-setting class G), and does not mark it as sold over the counter.
What pharmacies pay
Pharmacies pay $1.08 for 1 mL (1 × $1.084 per ML, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.
NADAC’s explanation codes for it: 1, calculated from the most recently completed pharmacy survey; 5, calculated based on package size.
What NADAC measures · NADAC explanation codes
The 10 labelers
| Labeler | NDCs | Pharmacies pay per unit |
|---|---|---|
| Dr. Reddy's Laboratories Inc. | 2 | $1.084 per ML filed |
| Amneal Pharmaceuticals LLC | 1 | $1.084 per ML filed |
| Ascend Laboratories, LLC | 1 | $1.084 per ML filed |
| Lifestar Pharma LLC | 1 | $1.084 per ML filed |
| Lupin Pharmaceuticals, Inc. | 1 | $1.084 per ML filed |
| Micro Labs Limited | 1 | $1.084 per ML filed |
| NorthStar RxLLC | 1 | $1.084 per ML filed |
| Ritedose Pharmaceuticals, LLC | 1 | $1.084 per ML filed |
| Sun Pharmaceutical Industries, Inc. | 1 | $1.084 per ML filed |
| Teva Pharmaceuticals USA, Inc. | 1 | $1.084 per ML filed |
All 11 NDCs, with labeler and price
- 00093-4085-63 · Teva Pharmaceuticals USA, Inc. · $1.084 per ML · eff. 2026-09-23 filed
- 42571-0408-92 · Micro Labs Limited · $1.084 per ML · eff. 2026-09-23 filed
- 43598-0605-56 · Dr. Reddy's Laboratories Inc. · $1.084 per ML · eff. 2026-09-23 filed
- 43598-0605-58 · Dr. Reddy's Laboratories Inc. · $1.084 per ML · eff. 2026-09-23 filed
- 47335-0171-49 · Sun Pharmaceutical Industries, Inc. · $1.084 per ML · eff. 2026-09-23 filed
- 65162-0914-46 · Amneal Pharmaceuticals LLC · $1.084 per ML · eff. 2026-09-23 filed
- 67877-0678-70 · Ascend Laboratories, LLC · $1.084 per ML · eff. 2026-09-23 filed
- 68180-0962-56 · Lupin Pharmaceuticals, Inc. · $1.084 per ML · eff. 2026-09-23 filed
- 70756-0604-56 · Lifestar Pharma LLC · $1.084 per ML · eff. 2026-09-23 filed
- 72603-0430-56 · NorthStar RxLLC · $1.084 per ML · eff. 2026-09-23 filed
- 76204-0029-56 · Ritedose Pharmaceuticals, LLC · $1.084 per ML · eff. 2026-09-23 filed
Other strengths, forms and brands
3 other products in the NADAC file share an FDA nonproprietary name with TOBRAMYCIN 300 MG/5 ML AMPULE.
| Product | Pharmacies pay per unit | Medicare per unit |
|---|---|---|
| TOBRAMYCIN 0.3% EYE DROP | $1.1081 per ML filed | We don’t know yet |
| TOBRAMYCIN 80 MG/2 ML VIAL | $0.83153 per ML filed | $1.1725 per ML derived |
| TOBRAMYCIN 300 MG/5 ML AMPULE this page | $1.084 per ML filed | $2.2808 per ML derived |
| TOBREX 0.3% EYE OINTMENT | $84.41452 per GM filed | $74.4502 per GM filed |
Part D is one average per brand and generic name, over every strength and form.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
Medicare Part D · DSD_PTD_RY26_P04_V10_DY24_BGM.csv · eff. 2024-01-01 to 2024-12-31 · as of 2026-06-25 · retrieved 2026-10-18
OpenBill calculation · october-2026-medicare-part-b-payment-limit-files-final.zip + october-2026-ndc-hcpcs-crosswalk-final.zip · Part B limit 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18) · Part B crosswalk 2026-10-01 to 2026-12-31 (file of 2026-09-17, retrieved 2026-10-18)
Compared with its class
The middle of its 11 NDCs’ NADAC prices is $1.084 per ML filed.
Of the 15 other products in FDA’s Aminoglycoside Antibacterial class priced per ML, 13 have a higher middle NADAC price and 2 a lower one. The one in the middle is TOBRAMYCIN-DEXAMETH OPHTH SUSP, at $4.1784 per ML filed (eff. 2026-09-23).
Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.
CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17
What Medicare paid
Medicare Part B’s payment limit for HCPCS J7682, for 2026-10-01 to 2026-12-31, comes to $2.28 for 1 mL, or $2.2808 per ML once converted to NADAC’s unit for this product.
Medicare Part B pays for an inhaled drug like this only in specific circumstances, such as when it is used with medical equipment like a nebulizer; most prescriptions filled at a pharmacy are paid by Part D.
The patient’s share under Part B (coinsurance, 20% of the limit, before deductibles and other coverage) is $2.2808 per 300 MG.
9 of the product’s 11 NDCs have this Medicare figure; the other 2 do not, and the interactive card says why for each.
Medicare's price is not your price.
What the Part B payment limit is · Converting it to the NADAC unit · How the spread is worked out
What to ask at the counter
None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.
- What is your cash price for 1 mL? Is it lower than what I would pay through my insurance?
- How much is in the package I am getting? This page uses 1 mL; your package may hold a different amount.
- If you have Medicare Part B: is this drug covered for me in this setting, and what is my share?
- These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.
Questions
- Why does this page start at 1 mL?
- The FDA package descriptions of this product’s NDCs give different amounts (280 mL, 1,120 mL, 1,960 mL). So the card starts at 1 ML; change it to match your prescription.
Related pages
Its pharmacologic class
Related in the same class
- TOBRAMYCIN-DEXAMETH OPHTH SUSP
- NEOMYCIN 500 MG TABLET
- TOBRADEX ST 0.3-0.05% EYE DROP
- AMIKACIN SULF 500 MG/2 ML VIAL
- ZYLET EYE DROPS