Why does this page start at 1 patch?

NADAC prices this product per EA, and the FDA NDC Directory lists 1 of its 2 NDCs (it does not list the other one) as dosage form “PATCH” with route “TRANSDERMAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. So the card starts at 1 patch, priced per patch, rather than guess how many make up a fill; change it to match your prescription.

TWIRLA 120-30 MCG/DAY PATCH

FDA nonproprietary name: levonorgestrel/ethinyl estradiol

For 1 patch

Pharmacies pay

$66.95 filed

1 × $66.95348 per EA

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

Medicare

We don’t know yet

No Medicare reference price. Part D: OpenBill did not match this NDC to a usable Medicare Part D spending row. Either Part D has none for it, or the rows that share its name could not safely be tied to it (for example, they mix units, routes or release forms, or the drug is sold over the counter, which Part D does not cover). Part B: This NDC is not in the current quarter’s Medicare Part B NDC-HCPCS crosswalk, so it has no Part B payment limit.

The spread

We don’t know yet

There is no Medicare figure to compare with, so there is no spread.

Cost-plus estimate

$81.99 estimated

$66.95 + $10.04 (15%) + $5.00 fee per fill = $81.99

This is a model, not a price any pharmacy quoted. Shipping is not included. How it is worked out

OpenBill calculation · nadac-national-average-drug-acquisition-cost-20261014.csv · NADAC eff. 2026-09-23 (file of 2026-10-14, retrieved 2026-10-17)

Open the interactive card Change the quantity, type what you were charged, and see every record in full.

What it is

TWIRLA 120-30 MCG/DAY PATCH is how the CMS NADAC file names this product. The FDA NDC Directory lists it as levonorgestrel/ethinyl estradiol, under the trade name “Twirla”.

FDA gives its dosage form as patch and its route as transdermal.

The labeler, the company named on the label, is Agile Therapeutics, Inc.

FDA lists it under 3 Established Pharmacologic Classes: Estrogen, Progestin and Progestin-containing Intrauterine System.

The NADAC file of 2026-10-14 prices it under 2 NDCs (National Drug Codes); the FDA directory lists 1 of them.

NADAC classes it as a brand-name drug (rate-setting class B), and does not mark it as sold over the counter.

What pharmacies pay

Pharmacies pay $66.95 for 1 patch (1 × $66.95348 per EA, rounded to the cent), by the CMS NADAC file of 2026-10-14; that price took effect on 2026-09-23. That is what pharmacies pay their suppliers, not what they charge you.

NADAC’s explanation code for it: 1, calculated from the most recently completed pharmacy survey.

What NADAC measures · NADAC explanation codes

All 2 NDCs

71671-0100-03 · Agile Therapeutics, Inc. · $66.95348 per EA · eff. 2026-09-23 filed
71671-0100-11 · not listed as a package in the FDA directory · $66.95348 per EA · eff. 2026-09-23 filed

Compared with its class

The middle of its 2 NDCs’ NADAC prices is $66.95348 per EA filed.

Of the 104 other products in FDA’s Estrogen class priced per EA, 5 have a higher middle NADAC price and 99 a lower one. The one in the middle is LYLLANA 0.075 MG PATCH, at $8.11285 per EA filed (eff. 2026-09-23).

Of the 65 other products in FDA’s Progestin class priced per EA, 2 have a higher middle NADAC price and 63 a lower one. The one in the middle is NORETHIN-ETH ESTRAD 1 MG-5 MCG, at $0.57994 per EA filed (eff. 2026-09-23).

Of the 9 other products in FDA’s Progestin-containing Intrauterine System class priced per EA, 0 have a higher middle NADAC price and 9 a lower one. The one in the middle is LEVONORGESTREL 1.5 MG TABLET, at $6.33055 per EA filed (eff. 2026-09-23).

Prices are compared per unit, whatever the strength or dose, and a class is not a list of substitutes.

CMS NADAC · nadac-national-average-drug-acquisition-cost-20261014.csv · eff. 2026-09-23 · as of 2026-10-14 · retrieved 2026-10-17

How the class comparison works

What Medicare paid

We don’t know yet; the card above says why.

Which Medicare figure OpenBill compares · How Part D is matched · How Part B is matched

What to ask at the counter

None of these figures is your price: what you pay depends on your pharmacy, your insurance, coupons and discounts.

What is your cash price for 1 patch? Is it lower than what I would pay through my insurance?
These are questions about price, not medical advice. Do not change or stop a medicine without talking to your prescriber or pharmacist.

Questions

Why does this page start at 1 patch?: NADAC prices this product per EA, and the FDA NDC Directory lists 1 of its 2 NDCs (it does not list the other one) as dosage form “PATCH” with route “TRANSDERMAL”. Only a tablet, capsule, lozenge or troche with route “ORAL”, or a tablet or film with route “SUBLINGUAL” or “BUCCAL”, starts at 30, and this is not one. So the card starts at 1 patch, priced per patch, rather than guess how many make up a fill; change it to match your prescription.

Its pharmacologic classes

Estrogen 121 products
Progestin 72 products
Progestin-containing Intrauterine System 10 products